Virus Expression Database

GSE108897

HIV-1 indcued genes in human monocyte-derived macrophages

Submitted by Mark A Wallet (University of Florida, USA) on Jan 08 2018

Platform: microarray – [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version]

Pubmed: 29437254

Summary HIV-1 infection of monocyte-derived macrophages does not elicit a detectable type I IFN response in vitro, however, previously published data has shown that blocking STAT1 and STAT3 inhibits HIV-1 replication. Here we test to see if low levels of IFN inducible genes are detectable in human monocyte-derived macrophages that have been infected with HIV-1 in vitro.

10 Samples

ID Title Cell Type Timepoint Reported Virus Virus Species Exclusion Reason
GSM2915659 Donor 1 Untreated macrophage  untreated Uninfected
GSM2915660 Donor 1 HIV macrophage  7 days HIV-1-AD Human immunodeficiency virus 1
GSM2915661 Donor 2 Untreated macrophage  untreated Uninfected
GSM2915662 Donor 2 HIV macrophage  7 days HIV-1-AD Human immunodeficiency virus 1
GSM2915663 Donor 3 Untreated macrophage  untreated Uninfected
GSM2915664 Donor 3 HIV macrophage  7 days HIV-1-AD Human immunodeficiency virus 1
GSM2915665 Donor 4 Untreated macrophage  untreated Uninfected
GSM2915666 Donor 4 HIV macrophage  7 days HIV-1-AD Human immunodeficiency virus 1
GSM2915667 Donor 5 Untreated macrophage  untreated Uninfected
GSM2915668 Donor 5 HIV macrophage  7 days HIV-1-AD Human immunodeficiency virus 1