Virus Expression Database
Submitted by Martin Tolstrup (Aarhus University, Denmark) on Jan 29 2018
Platform: microarray – [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
Pubmed: 29468194
Summary A clinical study evaluating the dosing of an oral HDACi panobinostat in patient infected with HIV-1. Dosing was 20 mg orally, 3 times weekly, every other week for a total of 8 weeks.
Gene expression was evaluated in whole PBMCs at baseline (Visit 2), after 3 doses (Visit 4), 4 weeks after dosing (Visit 12) and 6 months after dosing (Visit 13) using the Affymetrix HTA 2.0 gene expression chip
| ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
|---|---|---|---|---|---|---|
| GSM2967397 | PBMC at baseline, ID 01 | peripheral blood mononuclear cell  |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967398 | PBMC at Visit 4, ID 01 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967399 | PBMC at Visit 12, ID 01 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967400 | PBMC at Visit 13, ID 01 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967401 | PBMC at baseline, ID 02 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967402 | PBMC at Visit 4, ID 02 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967403 | PBMC at Visit 12, ID 02 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967404 | PBMC at Visit 13, ID 02 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967405 | PBMC at baseline, ID 04 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967406 | PBMC at Visit 4, ID 04 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967407 | PBMC at Visit 12, ID 04 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967408 | PBMC at Visit 13, ID 04 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967409 | PBMC at baseline, ID 05 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967410 | PBMC at Visit 4, ID 05 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967411 | PBMC at Visit 12, ID 05 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967412 | PBMC at Visit 13, ID 05 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967413 | PBMC at baseline, ID 06 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967414 | PBMC at Visit 4, ID 06 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967415 | PBMC at Visit 12, ID 06 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967416 | PBMC at Visit 13, ID 06 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967417 | PBMC at baseline, ID 07 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967418 | PBMC at Visit 4, ID 07 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967419 | PBMC at Visit 12, ID 07 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967420 | PBMC at Visit 13, ID 07 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967421 | PBMC at baseline, ID 08 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967422 | PBMC at Visit 4, ID 08 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967423 | PBMC at Visit 12, ID 08 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967424 | PBMC at Visit 13, ID 08 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967425 | PBMC at baseline, ID 09 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967426 | PBMC at Visit 4, ID 09 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967427 | PBMC at Visit 12, ID 09 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967428 | PBMC at Visit 13, ID 09 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967429 | PBMC at baseline, ID 10 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967430 | PBMC at Visit 4, ID 10 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967431 | PBMC at Visit 12, ID 10 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967432 | PBMC at Visit 13, ID 10 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967433 | PBMC at baseline, ID 12 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967434 | PBMC at Visit 4, ID 12 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967435 | PBMC at Visit 12, ID 12 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967436 | PBMC at Visit 13, ID 12 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967437 | PBMC at baseline, ID 14 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967438 | PBMC at Visit 4, ID 14 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967439 | PBMC at Visit 12, ID 14 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967440 | PBMC at Visit 13, ID 14 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967441 | PBMC at baseline, ID 15 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967442 | PBMC at Visit 4, ID 15 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967443 | PBMC at Visit 12, ID 15 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967444 | PBMC at Visit 13, ID 15 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967445 | PBMC at baseline, ID 17 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967446 | PBMC at Visit 4, ID 17 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967447 | PBMC at Visit 12, ID 17 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967448 | PBMC at Visit 13, ID 17 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967449 | PBMC at baseline, ID 18 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967450 | PBMC at Visit 4, ID 18 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967451 | PBMC at Visit 12, ID 18 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967452 | PBMC at Visit 13, ID 18 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |
| GSM2967453 | PBMC at baseline, ID 19 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | |
| GSM2967454 | PBMC at Visit 4, ID 19 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions after 3 doses panobinostat |
| GSM2967455 | PBMC at Visit 12, ID 19 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 4 wks after panobinostat course |
| GSM2967456 | PBMC at Visit 13, ID 19 | peripheral blood mononuclear cell |
chronic | HIV-1 | Human immunodeficiency virus 1 | Extra interventions 6 mos after panobinostat course |