Submitted by Andrew D Yurochko (LSUHSC-S, USA) on Nov 14 2007
Platform: microarray – [HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Summary Human cytomegalovirus induces a pro-inflammatory monocyte following infection. To begin to address how HCMV induces these rapid changes in infected monocytes, we examined the transcriptome of infected monocytes. Global transcriptional profiling using cDNA microarrays revealed a significant number of pro-inflammatory genes were upregulated within 4 hours post infection.
Keywords: Disease State
ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
---|---|---|---|---|---|---|
GSM242894 | Monocyte_HCMV-1 | monocyte | 4 hrs | HCMV (Towne) | Human betaherpesvirus 5 | |
GSM242895 | Monocyte_HCMV-2 | monocyte | 4 hrs | HCMV (Towne) | Human betaherpesvirus 5 | |
GSM242896 | Monocyte_HCMV-3 | monocyte | 4 hrs | HCMV (Towne) | Human betaherpesvirus 5 | |
GSM242897 | Monocyte_HCMV-4 | monocyte | 4 hrs | HCMV (Towne) | Human betaherpesvirus 5 | |
GSM242898 | Monocyte_HCMV-5 | monocyte | 4 hrs | HCMV (Towne) | Human betaherpesvirus 5 | |
GSM242899 | Monocyte_HCMV-6 | monocyte | 4 hrs | HCMV (Towne) | Human betaherpesvirus 5 | |
GSM287911 | Mock-infected monocyte, biological rep1 | monocyte | 4 hrs | Mock | Uninfected | |
GSM287912 | Mock-infected monocyte, biological rep2 | monocyte | 4 hrs | Mock | Uninfected | |
GSM287913 | Mock-infected monocyte, biological rep3 | monocyte | 4 hrs | Mock | Uninfected | |
GSM287914 | Mock-infected monocyte, biological rep4 | monocyte | 4 hrs | Mock | Uninfected | |
GSM287915 | Mock-infected monocyte, biological rep5 | monocyte | 4 hrs | Mock | Uninfected | |
GSM287916 | Mock-infected monocyte, biological rep6 | monocyte | 4 hrs | Mock | Uninfected |