Submitted by Li Yang (Chinese Academy of Sciences, China) on Nov 26 2018
Platform: ngs – Illumina NextSeq 500 (Homo sapiens)
Pubmed: 31031002
Summary RNase L–mediated rapid degradation of circRNAs is required for PKR activation in innate immune responses and linked to the autoimmune disease systemic lupus erythematosus.
ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
---|---|---|---|---|---|---|
GSM3489316 | HeLa ctrl poly(A)+ RNA | cervical adenocarcinoma cell line [HeLa ] | none | Uninfected | ||
GSM3489317 | HeLa poly(I:C) poly(A)+ RNA | cervical adenocarcinoma cell line [HeLa ] | none | Uninfected | Extra interventions poly(I:C) treated |
|
GSM3489322 | HeLa RNaseL KO ctrl poly(A)+ RNA | cervical adenocarcinoma cell line [HeLa ] | none | Uninfected | Extra interventions RNaseL KO |
|
GSM3489323 | HeLa RNaseL KO poly(I:C) poly(A)+ RNA | cervical adenocarcinoma cell line [HeLa ] | none | Uninfected | Extra interventions RNaseL KO, poly(I:C) treated |
|
GSM3489328 | HeLa wt ctrl poly(A)+ RNA replicate 1 | cervical adenocarcinoma cell line [HeLa ] | none | Uninfected | ||
GSM3489329 | HeLa wt ctrl poly(A)+ RNA replicate 2 | cervical adenocarcinoma cell line [HeLa ] | none | Uninfected | ||
GSM3489330 | HeLa wt EMCV poly(A)+ RNA replicate 1 | cervical adenocarcinoma cell line [HeLa ] | 24 hrs | EMCV | Cardiovirus A | |
GSM3489331 | HeLa wt EMCV poly(A)+ RNA replicate 2 | cervical adenocarcinoma cell line [HeLa ] | 24 hrs | EMCV | Cardiovirus A |