Virus Expression Database

GSE123541

Genome-wide RNA-seq and ATAC-seq analysis of an in vivo human immune response to acute Zika virus infection

Submitted by Aaron F Carlin (San Diego, USA) on Dec 10 2018

Platform: ngs – Illumina HiSeq 2000 (Homo sapiens)

Pubmed: 30596671

Summary A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infected with ZIKV while traveling to Caracas, Venezuela during the zika virus epidemic. Includes longitudinal RNA-seq and ATAC-seq characterization of innate and adaptive immune responses during an acute ZIKV infection.

35 Samples

ID Title Cell Type Timepoint Reported Virus Virus Species Exclusion Reason
GSM3506299 CD14dimCD16pos-Day03 monocyte  3 days Zika virus Data failed QC
pct_pseudoaligned is 15.1% (low fraction of usable reads)
GSM3506300 CD14dimCD16pos-Day06 monocyte  6 days Zika virus Data failed QC
pct_pseudoaligned is 16.8% (low fraction of usable reads)
GSM3506301 CD14dimCD16pos-Day17 monocyte  17 days Zika virus Data failed QC
pct_pseudoaligned is 16.3% (low fraction of usable reads)
GSM3506302 CD14dimCD16pos-Day48 monocyte  48 days Zika virus Data failed QC
pct_pseudoaligned is 11.1% (low fraction of usable reads)
GSM3506303 CD14posCD16neg-Day03 monocyte  3 days Zika virus Data failed QC
pct_pseudoaligned is 10.6% (low fraction of usable reads)
GSM3506304 CD14posCD16neg-Day06 monocyte  6 days Zika virus Data failed QC
pct_pseudoaligned is 13.7% (low fraction of usable reads)
GSM3506305 CD14posCD16neg-Day17 monocyte  17 days Zika virus Data failed QC
pct_pseudoaligned is 13.7% (low fraction of usable reads)
GSM3506306 CD14posCD16neg-Day48 monocyte  48 days Zika virus Data failed QC
pct_pseudoaligned is 11.4% (low fraction of usable reads)
GSM3506307 CD14posCD16pos-Day03  monocyte  3 days Zika virus Data failed QC
pct_pseudoaligned is 10.8% (low fraction of usable reads)
GSM3506308 CD14posCD16pos-Day06 monocyte  6 days Zika virus Data failed QC
pct_pseudoaligned is 14.3% (low fraction of usable reads)
GSM3506309 CD14posCD16pos-Day17 monocyte  17 days Zika virus Data failed QC
pct_pseudoaligned is 11.5% (low fraction of usable reads)
GSM3506310 CD14posCD16pos-Day48 monocyte  48 days Zika virus Data failed QC
pct_pseudoaligned is 9.0% (low fraction of usable reads)
GSM3506311 CD4Tcell-Day03  helper T-lymphocyte  3 days Zika virus Data failed QC
pct_pseudoaligned is 13.0% (low fraction of usable reads)
GSM3506312 CD4Tcell-Day06 helper T-lymphocyte  6 days Zika virus Data failed QC
pct_pseudoaligned is 10.9% (low fraction of usable reads)
GSM3506313 CD4Tcell-Day17 helper T-lymphocyte  17 days Zika virus Data failed QC
pct_pseudoaligned is 8.5% (low fraction of usable reads)
GSM3506314 CD4Tcell-Day48 helper T-lymphocyte  48 days Zika virus Data failed QC
pct_pseudoaligned is 8.1% (low fraction of usable reads)
GSM3506315 CD8Tcell-Day03 cytotoxic T-lymphocyte  3 days Zika virus Data failed QC
pct_pseudoaligned is 11.0% (low fraction of usable reads)
GSM3506316 CD8Tcell-Day06 cytotoxic T-lymphocyte  6 days Zika virus Data failed QC
pct_pseudoaligned is 11.9% (low fraction of usable reads)
GSM3506317 CD8Tcell-Day17 cytotoxic T-lymphocyte  17 days Zika virus Data failed QC
pct_pseudoaligned is 9.5% (low fraction of usable reads)
GSM3506318 CD8Tcell-Day48 cytotoxic T-lymphocyte  48 days Zika virus Data failed QC
pct_pseudoaligned is 10.6% (low fraction of usable reads)
GSM3506319 MyeloidDC-Day03  myeloid dendritic cell  3 days Zika virus Data failed QC
pct_pseudoaligned is 11.6% (low fraction of usable reads)
GSM3506320 MyeloidDC-Day06 myeloid dendritic cell  6 days Zika virus Data failed QC
pct_pseudoaligned is 8.9% (low fraction of usable reads)
GSM3506321 MyeloidDC-Day17 myeloid dendritic cell  17 days Zika virus Data failed QC
pct_pseudoaligned is 11.3% (low fraction of usable reads)
GSM3506322 MyeloidDC-Day48 myeloid dendritic cell  48 days Zika virus Data failed QC
pct_pseudoaligned is 8.6% (low fraction of usable reads)
GSM3506323 NK-Day03 natural killer cell  3 days Zika virus Data failed QC
pct_pseudoaligned is 13.2% (low fraction of usable reads)
GSM3506324 NK-Day06 natural killer cell  6 days Zika virus Data failed QC
pct_pseudoaligned is 14.7% (low fraction of usable reads)
GSM3506325 NK-Day17 natural killer cell  17 days Zika virus Data failed QC
pct_pseudoaligned is 11.8% (low fraction of usable reads)
GSM3506326 NK-Day48 natural killer cell  48 days Zika virus Data failed QC
pct_pseudoaligned is 9.3% (low fraction of usable reads)
GSM3506327 PBMC-Day03 peripheral blood mononuclear cell  3 days Zika virus Data failed QC
pct_pseudoaligned is 6.1% (low fraction of usable reads)
GSM3506328 PBMC-Day06 peripheral blood mononuclear cell  6 days Zika virus Data failed QC
pct_pseudoaligned is 6.3% (low fraction of usable reads)
GSM3506329 PBMC-Day17 peripheral blood mononuclear cell  17 days Zika virus Data failed QC
pct_pseudoaligned is 5.7% (low fraction of usable reads)
GSM3506330 PBMC-Day48 peripheral blood mononuclear cell  48 days Zika virus Data failed QC
pct_pseudoaligned is 9.9% (low fraction of usable reads)
GSM3506331 PlasmacytoidDC-Day03 plasmacytoid dendritic cell  3 days Zika virus Data failed QC
pct_pseudoaligned is 8.2% (low fraction of usable reads)
GSM3506332 PlasmacytoidDC-Day06 plasmacytoid dendritic cell  6 days Zika virus Data failed QC
pct_pseudoaligned is 7.7% (low fraction of usable reads)
GSM3506333 PlasmacytoidDC-Day48 plasmacytoid dendritic cell  48 days Zika virus Data failed QC
pct_pseudoaligned is 4.1% (low fraction of usable reads)