Virus Expression Database
Submitted by Sarah Aref (UCL Cancer Institute, United Kingdom) on May 28 2019
Platform: ngs – Illumina NextSeq 500 (Homo sapiens)
Pubmed: None listed
Summary The mechanisms by which oncolytic vaccine strains of measles virus exert their tumor selectivity are not well elucidated.
The goal of this study is to compare the gene expression profiles of MV-resistant MSC cell line (hTERT) and MV-susceptible MSC cell line (5H) before and after infection with MV (24 hours post infection)
Through RNA-seq we were able to identify genes that are potentially contribute to the resistant phenotype of hTERT cells compared to their malignant counterparts, 5H cells.
| ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
|---|---|---|---|---|---|---|
| GSM3822041 | hTERT_Uninfected_rep1 | hTERT (mesenchymal stem cell) | Uninfected | |||
| GSM3822042 | hTERT_Uninfected_rep2 | hTERT (mesenchymal stem cell) | Uninfected | |||
| GSM3822043 | hTERT_Uninfected_rep3 | hTERT (mesenchymal stem cell) | Uninfected | |||
| GSM3822044 | hTERT_MV_rep1 | hTERT (mesenchymal stem cell) | 24 hrs | Measles morbillivirus | ||
| GSM3822045 | hTERT_MV_rep2 | hTERT (mesenchymal stem cell) | 24 hrs | Measles morbillivirus | ||
| GSM3822046 | hTERT_MV_rep3 | hTERT (mesenchymal stem cell) | 24 hrs | Measles morbillivirus | ||
| GSM3822047 | 5H_Uninfected_rep1 | 5H (mesenchymal stem cell) | Uninfected | |||
| GSM3822048 | 5H_Uninfected_rep2 | 5H (mesenchymal stem cell) | Uninfected | |||
| GSM3822049 | 5H_Uninfected_rep3 | 5H (mesenchymal stem cell) | Uninfected | |||
| GSM3822050 | 5H_MV_rep1 | 5H (mesenchymal stem cell) | 24 hrs | Measles morbillivirus | ||
| GSM3822051 | 5H_MV_rep2 | 5H (mesenchymal stem cell) | 24 hrs | Measles morbillivirus | ||
| GSM3822052 | 5H_MV_rep3 | 5H (mesenchymal stem cell) | 24 hrs | Measles morbillivirus |