Virus Expression Database
Submitted by Yury A Bochkov (University Of Wisconsin-Madison, USA) on Oct 29 2008
Platform: microarray – [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Pubmed: 19710636
Summary Human Rhinovirus (HRV) infection can trigger exacerbations of asthma. Understanding of the mechanisms provoking airway inflammation and remodeling in asthma, as well as the pathogenic mechanisms of HRV infection and its association with asthma exacerbations, may offer significant opportunities for improved disease management. Genome-wide expression analysis of HRV type 1A-infected primary bronchial epithelial (PBE) cells from normal and asthmatic donors was performed to determine whether asthma is associated with a unique pattern of gene expression after HRV infection in vitro.
Keywords: response to rhinovirus infection
| ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
|---|---|---|---|---|---|---|
| GSM338272 | mock-infected, asthmatic S10 (U133 Plus 2.0 Array) | bronchial epithelial cell  |
16 hrs | mock | Uninfected | Extra interventions asthmatic |
| GSM338273 | mock-infected, asthmatic S12 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | mock | Uninfected | Extra interventions asthmatic |
| GSM338274 | mock-infected, asthmatic S16 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | mock | Uninfected | Extra interventions asthmatic |
| GSM338275 | mock-infected, asthmatic S17 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | mock | Uninfected | Extra interventions asthmatic |
| GSM338276 | mock-infected, asthmatic S18 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | mock | Uninfected | Extra interventions asthmatic |
| GSM338277 | HRV-infected, asthmatic S10 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A | Extra interventions asthmatic |
| GSM338278 | HRV-infected, asthmatic S12 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A | Extra interventions asthmatic |
| GSM338279 | HRV-infected, asthmatic S16 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A | Extra interventions asthmatic |
| GSM338280 | HRV-infected, asthmatic S17 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A | Extra interventions asthmatic |
| GSM338281 | HRV-infected, asthmatic S18 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A | Extra interventions asthmatic |
| GSM338282 | mock-infected, normal S13 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | mock | Uninfected | |
| GSM338283 | mock-infected, normal S14 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | mock | Uninfected | |
| GSM338284 | mock-infected, normal S15 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | mock | Uninfected | |
| GSM338285 | mock-infected, normal S7 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | mock | Uninfected | |
| GSM338286 | mock-infected, normal S8 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | mock | Uninfected | |
| GSM338287 | mock-infected, normal S9 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | mock | Uninfected | |
| GSM338288 | HRV-infected, normal S13 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A | |
| GSM338289 | HRV-infected, normal S14 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A | |
| GSM338290 | HRV-infected, normal S15 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A | |
| GSM338291 | HRV-infected, normal S7 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A | |
| GSM338292 | HRV-infected, normal S8 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A | |
| GSM338293 | HRV-infected, normal S9 (U133 Plus 2.0 Array) | bronchial epithelial cell |
16 hrs | HRV | Rhinovirus A |