Submitted by Michael Bonin (University Tuebingen, Germany) on Feb 13 2009
Platform: microarray – [HG-U133A] Affymetrix Human Genome U133A Array
Pubmed: 19951172
Summary Microarray analysis and quantitative real-time PCR revealed that TB40E infection of DCs led to changes of the gene expression pattern. A variety of pro-inflammatory cytokines and chemokines (CXCL10, CXCL11, CCL5), TLR3 and genes whose products function downstream of the TLR3 signalling pathway (e.g. IFN-α, IFN-β) were significantly upregulated.
ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
---|---|---|---|---|---|---|
GSM371008 | Immune Response of Immature Dendritic Cells after Infection with Human Cytomegalovirus Strain TB40E mock sample 1 | Immature dendritic cells | 24 hrs | mock | Uninfected | |
GSM371009 | Immune Response of Immature Dendritic Cells after Infection with Human Cytomegalovirus Strain TB40E mock sample 2 | Immature dendritic cells | 24 hrs | mock | Uninfected | |
GSM371010 | Immune Response of Immature Dendritic Cells after Infection with Human Cytomegalovirus Strain TB40E mock sample 3 | Immature dendritic cells | 24 hrs | mock | Uninfected | |
GSM371011 | Immune Response of Immature Dendritic Cells after Infection with Human Cytomegalovirus Strain TB40E TB treated sample 1 | Immature dendritic cells | 24 hrs | HCMV Strain TB40E | Human betaherpesvirus 5 | |
GSM371012 | Immune Response of Immature Dendritic Cells after Infection with Human Cytomegalovirus Strain TB40E TB treated sample 2 | Immature dendritic cells | 24 hrs | HCMV Strain TB40E | Human betaherpesvirus 5 | |
GSM371013 | Immune Response of Immature Dendritic Cells after Infection with Human Cytomegalovirus Strain TB40E TB treated sample 3 | Immature dendritic cells | 24 hrs | HCMV Strain TB40E | Human betaherpesvirus 5 |