GSE150392

RNA-Seq of Human iPSC-cardiomyocytes infected with SARS-CoV-2

Submitted by yizhou wang (cedars sinai medical center, USA) on May 12 2020

Platform: ngs – Illumina NextSeq 500 (Homo sapiens)

Pubmed: 32835305, 33805016

Summary Coronavirus disease 2019 (COVID-19) is a viral pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is predominantly defined by respiratory symptoms, but cardiac complications including arrhythmias, heart failure, and viral myocarditis are also prevalent. Although the systemic ischemic and inflammatory responses caused by COVID-19 can detrimentally affect cardiac function, the direct impact of SARS-CoV-2 infection on human cardiomyocytes is not well understood.

6 Samples

ID	Title	Cell Type	Timepoint	Reported Virus	Virus Species	Exclusion Reason
GSM4548303	SARS-CoV-2 Infected hiPSC-CMs (rep 1)	cardiomyocyte cell line	72 hrs	SARS-CoV-2	Severe acute respiratory syndrome-related coronavirus
GSM4548304	SARS-CoV-2 Infected hiPSC-CMs (rep 2)	cardiomyocyte cell line	72 hrs	SARS-CoV-2	Severe acute respiratory syndrome-related coronavirus
GSM4548305	SARS-CoV-2 Infected hiPSC-CMs (rep 3)	cardiomyocyte cell line	72 hrs	SARS-CoV-2	Severe acute respiratory syndrome-related coronavirus
GSM4548306	Mock hiPSC-CMs (rep 1)	cardiomyocyte cell line		Mock	Uninfected
GSM4548307	Mock hiPSC-CMs (rep 2)	cardiomyocyte cell line		Mock	Uninfected
GSM4548308	Mock hiPSC-CMs (rep 3)	cardiomyocyte cell line		Mock	Uninfected