Virus Expression Database
Submitted by Piroska Devay (NIBRI, USA) on May 03 2009
Platform: microarray – [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Pubmed: 19932913
Summary Cyclophilin binding drugs, NIM811 and cyclosporin A (CsA), inhibit the replication of HCV replicon.
We investigated the mode of action of these drugs and identified host factors essential for HCV replication in a subgenomic replicon model.
| ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
|---|---|---|---|---|---|---|
| GSM399780 | Huh7 cells cultured for 12 hours rep1 | hepatoma cell line  [Huh-7  ] |
12 hrs | naïve | Uninfected | |
| GSM399781 | Huh7 cells cultured for 12 hours rep2 | hepatoma cell line [Huh-7 ] |
12 hrs | naïve | Uninfected | |
| GSM399782 | Huh7 cells cultured for 12 hours rep3 | hepatoma cell line [Huh-7 ] |
12 hrs | naïve | Uninfected | |
| GSM399783 | Huh7 cells treated with 5uM NIM811 and cultured for 12 hours rep1 | hepatoma cell line [Huh-7 ] |
12 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399784 | Huh7 cells treated with 5uM NIM811 and cultured for 12 hours rep2 | hepatoma cell line [Huh-7 ] |
12 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399785 | Huh7 cells treated with 5uM NIM811 and cultured for 12 hours rep3 | hepatoma cell line [Huh-7 ] |
12 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399786 | Huh7 cells treated with 5uM CsA and cultured for 12 hours rep1 | hepatoma cell line [Huh-7 ] |
12 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399787 | Huh7 cells treated with 5uM CsA and cultured for 12 hours rep2 | hepatoma cell line [Huh-7 ] |
12 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399788 | Huh7 cells treated with 5uM CsA and cultured for 12 hours rep3 | hepatoma cell line [Huh-7 ] |
12 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399789 | Huh7 cells cultured for 24 hours rep1 | hepatoma cell line [Huh-7 ] |
24 hrs | naïve | Uninfected | |
| GSM399790 | Huh7 cells cultured for 24 hours rep2 | hepatoma cell line [Huh-7 ] |
24 hrs | naïve | Uninfected | |
| GSM399791 | Huh7 cells cultured for 24 hours rep3 | hepatoma cell line [Huh-7 ] |
24 hrs | naïve | Uninfected | |
| GSM399792 | Huh7 cells treated with 5uM NIM811 and cultured for 24 hours rep1 | hepatoma cell line [Huh-7 ] |
24 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399793 | Huh7 cells treated with 5uM NIM811 and cultured for 24 hours rep2 | hepatoma cell line [Huh-7 ] |
24 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399794 | Huh7 cells treated with 5uM NIM811 and cultured for 24 hours rep3 | hepatoma cell line [Huh-7 ] |
24 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399795 | Huh7 cells treated with 5uM CsA and cultured for 24 hours rep1 | hepatoma cell line [Huh-7 ] |
24 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399796 | Huh7 cells treated with 5uM CsA and cultured for 24 hours rep2 | hepatoma cell line [Huh-7 ] |
24 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399797 | Huh7 cells cultured for 48 hours rep1 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | |
| GSM399798 | Huh7 cells cultured for 48 hours rep2 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | |
| GSM399799 | Huh7 cells cultured for 48 hours rep3 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | |
| GSM399800 | Huh7 cells treated with 5uM NIM811 and cultured for 48 hours rep1 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399801 | Huh7 cells treated with 5uM NIM811 and cultured for48 hours rep2 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399802 | Huh7 cells treated with 5uM NIM811 and cultured for 48 hours rep3 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399803 | Huh7 cells treated with 5uM CsA and cultured for 48 hours rep1 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399804 | Huh7 cells treated with 5uM CsA and cultured for 48 hours rep2 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399805 | Huh7 cells treated with 5uM CsA and cultured for 48 hours rep3 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399806 | Clone A cells cultured for 12 hours rep1 | hepatoma cell line [Huh-7 ] |
12 hrs | HCV replicon | Hepacivirus C | |
| GSM399807 | Clone A cells cultured for 12 hours rep2 | hepatoma cell line [Huh-7 ] |
12 hrs | HCV replicon | Hepacivirus C | |
| GSM399808 | Clone A cells cultured for 12 hours rep3 | hepatoma cell line [Huh-7 ] |
12 hrs | HCV replicon | Hepacivirus C | |
| GSM399809 | Clone A cells treated with 5uM NIM811 and cultured for 12 hours rep1 | hepatoma cell line [Huh-7 ] |
12 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399810 | Clone A cells treated with 5uM NIM811 and cultured for 12 hours rep2 | hepatoma cell line [Huh-7 ] |
12 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399811 | Clone A cells treated with 5uM NIM811 and cultured for 12 hours rep3 | hepatoma cell line [Huh-7 ] |
12 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399812 | Clone A cells treated with 5uM CsA and cultured for 12 hours rep1 | hepatoma cell line [Huh-7 ] |
12 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399813 | Clone A cells treated with 5uM CsA and cultured for 12 hours rep2 | hepatoma cell line [Huh-7 ] |
12 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399814 | Clone A cells treated with 5uM CsA and cultured for 12 hours rep3 | hepatoma cell line [Huh-7 ] |
12 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399815 | Clone A cells cultured for 24 hours rep1 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | |
| GSM399816 | Clone A cells cultured for 24 hours rep2 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | |
| GSM399817 | Clone A cells cultured for 24 hours rep3 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | |
| GSM399818 | Clone A cells treated with 5uM NIM811 and cultured for 24 hours rep1 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399819 | Clone A cells treated with 5uM NIM811 and cultured for 24 hours rep2 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399820 | Clone A cells treated with 5uM NIM811 and cultured for 24 hours rep3 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399821 | Clone A cells treated with 5uM CsA and cultured for 24 hours rep1 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399822 | Clone A cells treated with 5uM CsA and cultured for 24 hours rep2 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399823 | Clone A cells treated with 5uM CsA and cultured for 24 hours rep3 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399824 | Clone A cells cultured for 48 hours rep1 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | |
| GSM399825 | Clone A cells cultured for 48 hours rep2 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | |
| GSM399826 | Clone A cells cultured for 48 hours rep3 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | |
| GSM399827 | Clone A cells treated with 5uM NIM811 and cultured for 48 hours rep1 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399828 | Clone A cells treated with 5uM NIM811 and cultured for 48 hours rep2 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399829 | Clone A cells treated with 5uM NIM811 and cultured for 48 hours rep3 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399830 | Clone A cells treated with 5uM CsA and cultured for 48 hours rep1 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399831 | Clone A cells treated with 5uM CsA and cultured for 48 hours rep2 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399832 | Clone A cells treated with 5uM CsA and cultured for 48 hours rep3 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399833 | Huh7 cells cultured for 48 hours rep4 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | |
| GSM399834 | Huh7 cells cultured for 48 hours rep5 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | |
| GSM399835 | Huh7 cells cultured for 48 hours rep6 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | |
| GSM399836 | Clone A cells cultured for 48 hours rep4 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | |
| GSM399837 | Clone A cells cultured for 48 hours rep5 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | |
| GSM399838 | Clone A cells cultured for 48 hours rep6 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | |
| GSM399839 | Huh7 cells treated with 1uM CsA and cultured for 48 hours rep1 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399840 | Huh7 cells treated with 1uM CsA and cultured for 48 hours rep2 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399841 | Huh7 cells treated with 1uM CsA and cultured for 48 hours rep3 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399842 | Huh7 cells treated with 5uM CsA and cultured for 48 hours rep4 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399843 | Huh7 cells treated with 5uM CsA and cultured for 48 hours rep5 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399844 | Huh7 cells treated with 5uM CsA and cultured for 48 hours rep6 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions CsA |
| GSM399845 | Huh7 cells treated with 1uM NIM811 and cultured for 48 hours rep1 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399846 | Huh7 cells treated with 1uM NIM811 and cultured for48 hours rep2 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399847 | Huh7 cells treated with 1uM NIM811 and cultured for 48 hours rep3 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399848 | Huh7 cells treated with 5uM NIM811 and cultured for 48 hours rep4 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399849 | Huh7 cells treated with 5uM NIM811 and cultured for48 hours rep5 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399850 | Huh7 cells treated with 5uM NIM811 and cultured for 48 hours rep6 | hepatoma cell line [Huh-7 ] |
48 hrs | naïve | Uninfected | Extra interventions NIM811 |
| GSM399851 | Clone A cells treated with 1uM CsA and cultured for 24 hours rep1 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399852 | Clone A cells treated with 1uM CsA and cultured for 24 hours rep2 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399853 | Clone A cells treated with 1uM CsA and cultured for 24 hours rep3 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399854 | Clone A cells treated with 5uM CsA and cultured for 24 hours rep4 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399855 | Clone A cells treated with 5uM CsA and cultured for 24 hours rep5 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399856 | Clone A cells treated with 5uM CsA and cultured for 24 hours rep6 | hepatoma cell line [Huh-7 ] |
24 hrs | HCV replicon | Hepacivirus C | Extra interventions CsA |
| GSM399857 | Clone A cells treated with 1uM NIM811 and cultured for 48 hours rep1 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399858 | Clone A cells treated with 1uM NIM811 and cultured for 48 hours rep2 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399859 | Clone A cells treated with 1uM NIM811 and cultured for 48 hours rep3 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399860 | Clone A cells treated with 5uM NIM811 and cultured for 48 hours rep4 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |
| GSM399861 | Clone A cells treated with 5uM NIM811 and cultured for 48 hours rep5 | hepatoma cell line [Huh-7 ] |
48 hrs | HCV replicon | Hepacivirus C | Extra interventions NIM811 |