Virus Expression Database

GSE162736

SARS-CoV-2 infects human pluripotent stem cell-derived cardiomyocytes, impairing electrical and mechanical function

Submitted by Jr (University of Washington, USA) on Dec 06 2020

Platform: ngs – Illumina NovaSeq 6000 (Homo sapiens)

Pubmed: 33657418

Summary RNA-sequencing used to investigate the transcriptome response to Sars-cov-2 in ESC differentiated female cardiomyocytes and iPSC differentated male cardiomyctes

48 Samples

ID Title Cell Type Timepoint Reported Virus Virus Species Exclusion Reason
GSM4958687 G001_Gale105_E_1e-1_M_48_1 cardiomyocyte cell line  Mock Uninfected
GSM4958688 G002_Gale105_E_1e-1_M_48_2 cardiomyocyte cell line  Mock Uninfected
GSM4958689 G003_Gale105_E_1e-1_M_48_3 cardiomyocyte cell line  Mock Uninfected
GSM4958690 G004_Gale105_E_1e-1_I_48_1 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958691 G005_Gale105_E_1e-1_I_48_2 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958692 G006_Gale105_E_1e-1_I_48_3 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958693 G007_Gale105_I_1e-1_M_48_1 cardiomyocyte cell line  Mock Uninfected
GSM4958694 G008_Gale105_I_1e-1_M_48_2 cardiomyocyte cell line  Mock Uninfected
GSM4958695 G009_Gale105_I_1e-1_M_48_3 cardiomyocyte cell line  Mock Uninfected
GSM4958696 G010_Gale105_I_1e-1_I_48_1 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958697 G011_Gale105_I_1e-1_I_48_2 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958698 G012_Gale105_I_1e-1_I_48_3 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958699 G013_Gale105_E_1e-1_M_72_1 cardiomyocyte cell line  Mock Uninfected
GSM4958700 G014_Gale105_E_1e-1_M_72_2 cardiomyocyte cell line  Mock Uninfected
GSM4958701 G015_Gale105_E_1e-1_M_72_3 cardiomyocyte cell line  Mock Uninfected
GSM4958702 G016_Gale105_E_1e-1_I_72_1 cardiomyocyte cell line  72 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus Data failed QC
pct_pseudoaligned is 17.9% (low fraction of usable reads)
GSM4958703 G017_Gale105_E_1e-1_I_72_2 cardiomyocyte cell line  72 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958704 G018_Gale105_E_1e-1_I_72_3 cardiomyocyte cell line  72 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958705 G019_Gale105_I_1e-1_M_72_1 cardiomyocyte cell line  Mock Uninfected
GSM4958706 G020_Gale105_I_1e-1_M_72_2 cardiomyocyte cell line  Mock Uninfected
GSM4958707 G021_Gale105_I_1e-1_M_72_3 cardiomyocyte cell line  Mock Uninfected
GSM4958708 G022_Gale105_I_1e-1_I_72_1 cardiomyocyte cell line  72 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958709 G023_Gale105_I_1e-1_I_72_2 cardiomyocyte cell line  72 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958710 G024_Gale105_I_1e-1_I_72_3 cardiomyocyte cell line  72 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958711 G025_Gale105_E_5_M_24_1 cardiomyocyte cell line  Mock Uninfected
GSM4958712 G026_Gale105_E_5_M_24_2 cardiomyocyte cell line  Mock Uninfected
GSM4958713 G027_Gale105_E_5_M_24_3 cardiomyocyte cell line  Mock Uninfected
GSM4958714 G028_Gale105_E_5_I_24_1 cardiomyocyte cell line  24 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus Data failed QC
pct_pseudoaligned is 14.7% (low fraction of usable reads)
GSM4958715 G029_Gale105_E_5_I_24_2 cardiomyocyte cell line  24 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus Data failed QC
pct_pseudoaligned is 14.8% (low fraction of usable reads)
GSM4958716 G030_Gale105_E_5_I_24_3 cardiomyocyte cell line  24 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958717 G031_Gale105_I_5_M_24_1 cardiomyocyte cell line  Mock Uninfected
GSM4958718 G032_Gale105_I_5_M_24_2 cardiomyocyte cell line  Mock Uninfected
GSM4958719 G033_Gale105_I_5_M_24_3 cardiomyocyte cell line  Mock Uninfected
GSM4958720 G034_Gale105_I_5_I_24_1 cardiomyocyte cell line  24 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958721 G035_Gale105_I_5_I_24_2 cardiomyocyte cell line  24 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958722 G036_Gale105_I_5_I_24_3 cardiomyocyte cell line  24 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958723 G037_Gale105_E_5_M_48_1 cardiomyocyte cell line  Mock Uninfected
GSM4958724 G038_Gale105_E_5_M_48_2 cardiomyocyte cell line  Mock Uninfected
GSM4958725 G039_Gale105_E_5_M_48_3 cardiomyocyte cell line  Mock Uninfected
GSM4958726 G040_Gale105_E_5_I_48_1 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus Data failed QC
pct_pseudoaligned is 16.1% (low fraction of usable reads)
GSM4958727 G041_Gale105_E_5_I_48_2 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus Data failed QC
pct_pseudoaligned is 14.0% (low fraction of usable reads)
GSM4958728 G042_Gale105_E_5_I_48_3 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus Data failed QC
pct_pseudoaligned is 16.5% (low fraction of usable reads)
GSM4958729 G043_Gale105_I_5_M_48_1 cardiomyocyte cell line  Mock Uninfected
GSM4958730 G044_Gale105_I_5_M_48_2 cardiomyocyte cell line  Mock Uninfected
GSM4958731 G045_Gale105_I_5_M_48_3 cardiomyocyte cell line  Mock Uninfected
GSM4958732 G046_Gale105_I_5_I_48_1 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958733 G047_Gale105_I_5_I_48_2 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus
GSM4958734 G048_Gale105_I_5_I_48_3 cardiomyocyte cell line  48 hrs SARS-CoV-2 Severe acute respiratory syndrome-related coronavirus