Virus Expression Database
Submitted by Maria Garofalo (IRCCS Mondino Foundation, Italy) on Jan 06 2021
Platform: ngs – Illumina NextSeq 500 (Homo sapiens)
Pubmed: 34022369
Summary SARS-Cov-2 infection is frequently associated with Nervous System (NS) manifestations. However, it is not clear how SARS-CoV-2 can cause neurological dysfunctions and which molecular processes affects. In this work, we examined the frontal cortex tissue of patients who died of COVID-19 for the presence of SARS-CoV-2, comparing qRT-PCR with ddPCR. We also investigated the transcriptomic profile of frontal cortex from COVID-19 patients and matched controls by RNA-seq analysis to characterize the transcriptional signature.
| ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
|---|---|---|---|---|---|---|
| GSM5006430 | BB47: CTRL sample 47 | frontal lobe  |
Healthy | Uninfected | ||
| GSM5006431 | BB118: CTRL sample 118 | frontal lobe |
Healthy | Uninfected | ||
| GSM5006432 | BB120: CTRL sample 120 | frontal lobe |
Healthy | Uninfected | ||
| GSM5006433 | BB138: CTRL sample 138 | frontal lobe |
Healthy | Uninfected | ||
| GSM5006434 | BB236: CTRL sample 236 | frontal lobe |
Healthy | Uninfected | ||
| GSM5006435 | BB247: CTRL sample 247 | frontal lobe |
Healthy | Uninfected | ||
| GSM5006436 | BB271: CTRL sample 271 | frontal lobe |
Healthy | Uninfected | ||
| GSM5006437 | COV1: COVID sample 1 | frontal lobe |
COVID-19 | Severe acute respiratory syndrome-related coronavirus | Data failed QCpseudoaligned_reads is 1133403 (low number of usable reads) |
|
| GSM5006438 | COV3: COVID sample 3 | frontal lobe |
COVID-19 | Severe acute respiratory syndrome-related coronavirus | Data failed QCpct_pseudoaligned is 15.4% (low fraction of usable reads) |
|
| GSM5006439 | COV4: COVID sample 4 | frontal lobe |
COVID-19 | Severe acute respiratory syndrome-related coronavirus | ||
| GSM5006440 | COV5: COVID sample 5 | frontal lobe |
COVID-19 | Severe acute respiratory syndrome-related coronavirus | Data failed QCpseudoaligned_reads is 1233423 (low number of usable reads) |
|
| GSM5006441 | COV6: COVID sample 6 | frontal lobe |
COVID-19 | Severe acute respiratory syndrome-related coronavirus | Data failed QCpct_pseudoaligned is 14.1% (low fraction of usable reads) |
|
| GSM5006442 | COV7: COVID sample 7 | frontal lobe |
COVID-19 | Severe acute respiratory syndrome-related coronavirus | ||
| GSM5006443 | COV8: COVID sample 8 | frontal lobe |
COVID-19 | Severe acute respiratory syndrome-related coronavirus | ||
| GSM5006444 | COV9: COVID sample 9 | frontal lobe |
COVID-19 | Severe acute respiratory syndrome-related coronavirus | ||
| GSM5006445 | COV10: COVID sample 10 | frontal lobe |
COVID-19 | Severe acute respiratory syndrome-related coronavirus |