Submitted by Philip Hitchins Schwartz (Children's Hospital of Orange County, USA) on Dec 07 2009
Platform: microarray – [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Pubmed: 20071566
Summary Our results suggest that HCMV infection disrupts the self-renewal capacity of NPCs and influences their differentiation.
Whole genome expression analysis revealed many changes in cellular gene expression, including downregulation of genes pertinent to the neuronal lineage.
ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
---|---|---|---|---|---|---|
GSM480450 | mock-infected, biological rep1 | neural stem cell | mock | Uninfected | ||
GSM480451 | mock-infected, biological rep2 | neural stem cell | mock | Uninfected | ||
GSM480452 | 4 hours post-infection, biological rep1 | neural stem cell | 4 hrs | HCMV | Human betaherpesvirus 5 | |
GSM480453 | 4 hours post-infection, biological rep2 | neural stem cell | 4 hrs | HCMV | Human betaherpesvirus 5 | |
GSM480454 | 12 hours post-infection, biological rep1 | neural stem cell | 12 hrs | HCMV | Human betaherpesvirus 5 | |
GSM480455 | 12 hours post-infection, biological rep2 | neural stem cell | 12 hrs | HCMV | Human betaherpesvirus 5 | |
GSM480456 | 24 hours post-infection, biological rep1 | neural stem cell | 24 hrs | HCMV | Human betaherpesvirus 5 | |
GSM480457 | 24 hours post-infection, biological rep2 | neural stem cell | 24 hrs | HCMV | Human betaherpesvirus 5 |