GSE20200

Exon-Level Expression Data from Primary B Cells, Early Proliferating EBV-infected B Cells and Lymphoblastoid Cell Lines

Submitted by Luftig Laboratory (Duke University, USA) on Feb 04 2010

Platform: microarray – [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]

Pubmed: 21147465, 22855490

Summary Eptstein-Barr Virus, an oncogenic herpesvirus, infects and immortalizes human B cells in culture into indefinitely-proliferating LCLs. We examined the gene expression of primary B cells during the process of infection and growth transformation at the exon level to analyze early and late virus-induced changes in expression and exon usage.

12 Samples

ID	Title	Cell Type	Timepoint	Reported Virus	Virus Species	Exclusion Reason
GSM506714	B Cell 1	B-lymphocyte		none	Uninfected
GSM506715	B Cell 2	B-lymphocyte		none	Uninfected
GSM506716	B Cell 3	B-lymphocyte		none	Uninfected
GSM506717	B Cell 4	B-lymphocyte		none	Uninfected
GSM506718	Proliferating 1	B-lymphocyte	early proliferating	EBV	Human gammaherpesvirus 4
GSM506719	Proliferating 2	B-lymphocyte	early proliferating	EBV	Human gammaherpesvirus 4
GSM506720	Proliferating 3	B-lymphocyte	early proliferating	EBV	Human gammaherpesvirus 4
GSM506721	Proliferating 4	B-lymphocyte	early proliferating	EBV	Human gammaherpesvirus 4
GSM506722	LCL 1	B-lymphocyte	transformed			Molecular biology transformed
GSM506723	LCL 2	B-lymphocyte	transformed			Molecular biology transformed
GSM506724	LCL 3	B-lymphocyte	transformed			Molecular biology transformed
GSM506725	LCL 4	B-lymphocyte	transformed			Molecular biology transformed