Virus Expression Database
Submitted by Damien Chaussabel (Baylor Institute for Immunology Research, USA) on Dec 06 2011
Platform: microarray – [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Pubmed: 22398282
Summary To study the transcriptional profile of patients with acute RSV or Influenza infection,children of median age 2.4 months (range 1.5-8.6) hospitalized with acute RSV and influenza virus infection were offered study enrollment after microbiologic confirmation of the diagnosis. Blood samples were collected from them within 42-72 hours of hospitalization. We excluded children with suspected or proven polymicrobial infections, with underlying chronic medical conditions (i.e congenital heart disease, renal insufficiency), with immunodeficiency, or those who received systemic steroids or other immunomodulatory therapies. The RSV cohort consisted of 51 patients with median age of 2 months (range 1.5-3.9) and the influenza cohort had 28 patients with median age of 5.5 months (range 1.4-21). Control samples were obtained from healthy children undergoing elective surgical procedures or at outpatient clinic visits. To exclude viral co-infections we performed nasopharyngeal viral cultures of all subjects. We recruited 10 control patients for the RSV cohort with median age of 6.7 months (range 5-10), and 12 control patients for the influenza cohort with median age of18.5 months (range 10.5-26).
| ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
|---|---|---|---|---|---|---|
| GSM844133 | infant_rsv_508 | peripheral blood mononuclear cell  |
rsv | Human orthopneumovirus | ||
| GSM844134 | infant_rsv_511 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844135 | infant_rsv_569 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844136 | infant_healthy_3(control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844137 | infant_healthy_7 (control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844138 | infant_healthy_19N (control for rsv) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844139 | infant_healthy_19N (control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844140 | infant_healthy_25N (control for rsv) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844141 | infant_healthy_25N (control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844142 | infant_healthy_27N (control for rsv) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844143 | infant_healthy_27N (control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844144 | infant_healthy_45 (control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844145 | infant_rsv_53 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844146 | infant_rsv_56 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844147 | infant_influenza_87 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844148 | infant_influenza_92 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844149 | infant_influenza_95 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844150 | infant_influenza_101 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844151 | infant_influenza_104 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844152 | infant_influenza_105 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844153 | infant_influenza_107 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844154 | infant_influenza_108 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844155 | infant_influenza_112 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844156 | infant_influenza_114 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844157 | infant_rsv_119 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844158 | infant_rsv_126 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844159 | infant_rsv_127 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844160 | infant_influenza_128 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844161 | infant_influenza_132 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844162 | infant_rsv_134 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844163 | infant_rsv_137 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844164 | infant_rsv_138 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844165 | infant_rsv_140 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844166 | infant_rsv_141 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844167 | infant_rsv_142 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844168 | infant_rsv_144 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844169 | infant_rsv_145 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844170 | infant_healthy_162 (control for rsv) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844171 | infant_healthy_174 (control for rsv) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844172 | infant_rsv_231 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844173 | infant_rsv_236 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844174 | infant_rsv_234 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844175 | infant_rsv_238 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844176 | infant_rsv_240 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844177 | infant_rsv_243 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844178 | infant_rsv_246 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844179 | infant_influenza_259 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844180 | infant_rsv_280 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844181 | infant_rsv_283 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844182 | infant_rsv_285 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844183 | infant_rsv_292 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844184 | infant_rsv_296 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844185 | infant_rsv_307 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844186 | infant_influenza_311 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844187 | infant_rsv_312 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844188 | infant_rsv_313 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844189 | infant_rsv_314 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844190 | infant_rsv_317 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844191 | infant_influenza_320 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844192 | infant_rsv_322 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844193 | infant_rsv_324 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844194 | infant_healthy_391 (control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844195 | infant_healthy_392 (control for rsv) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844196 | infant_healthy_392 (control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844197 | infant_healthy_397 (control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844198 | infant_healthy_403 (control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844199 | infant_healthy_408(control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844200 | infant_healthy_409 (control for rsv) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844201 | infant_healthy_414 (control for influenza) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844202 | infant_rsv_443 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844203 | infant_healthy_462 (control for rsv) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844204 | infant_healthy_482 (control for rsv) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844205 | infant_healthy_483 (control for rsv) | peripheral blood mononuclear cell |
healthy | Uninfected | ||
| GSM844206 | infant_rsv_492 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844207 | infant_rsv_495 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844208 | infant_rsv_497 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844209 | infant_rsv_498 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | Data failed QCall_probeset_mad_residual_mean is 0.890285 (poor normalization, above threshold of 0.80) |
|
| GSM844210 | infant_rsv_499 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844211 | infant_rsv_501 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844212 | infant_rsv_506 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844213 | infant_rsv_510 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844214 | infant_rsv_514 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844215 | infant_rsv_515 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844216 | infant_rsv_516 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844217 | infant_influenza_517 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844218 | infant_influenza_519 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844219 | infant_influenza_524 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844220 | infant_rsv_526 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844221 | infant_influenza_527 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844222 | infant_rsv_528 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844223 | infant_influenza_530 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844224 | infant_influenza_532 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844225 | infant_influenza_533 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844226 | infant_influenza_536 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844227 | infant_influenza_540 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844228 | infant_influenza_542 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844229 | infant_rsv_545 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844230 | infant_rsv_546 | peripheral blood mononuclear cell |
rsv | Human orthopneumovirus | ||
| GSM844231 | infant_influenza_553 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844232 | infant_influenza_560 | peripheral blood mononuclear cell |
influenza | Influenza A virus | ||
| GSM844233 | infant_influenza_572 | peripheral blood mononuclear cell |
influenza | Influenza A virus |