Submitted by Pilib Ó Broin (Albert Einstein College of Medicine, USA) on May 22 2013
Platform: microarray – [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Pubmed: 24310299
Summary We study the global gene expression profiles of BKV viremia and nephropathy patients using microarrays in order to better understand the immunologic response to polyomavirus BK (BKV).
BKV has become increasingly prevalent since the introduction of more potent immunosuppressive agents. It has been shown that as many as 30% of renal transplant recipients develop asymptomatic viral shedding in the urine shortly after transplant, 10-20% have viremia, and as many as 1-10% can go on to develop overt nephropathy (BKVN) that might lead to graft loss. To date, the genomics of BKV viremia and BKVN have not been investigated thoroughly by microarray.
ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
---|---|---|---|---|---|---|
GSM1146679 | Blood_BKV_1 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146680 | Blood_BKV_2 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146681 | Blood_BKV_3 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146682 | Blood_BKV_4 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146683 | Blood_BKV_5 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146684 | Blood_BKV_6 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146685 | Blood_BKV_7 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146686 | Blood_BKV_8 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146687 | Blood_Control_1 | peripheral blood | control | Uninfected | ||
GSM1146688 | Blood_PreBKV_1 | peripheral blood | pre-BKV | Uninfected | ||
GSM1146689 | Blood_Control_2 | peripheral blood | control | Uninfected | ||
GSM1146690 | Blood_PreBKV_2 | peripheral blood | pre-BKV | Uninfected | ||
GSM1146691 | Blood_BKV_9 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146692 | Blood_Control_3 | peripheral blood | control | Uninfected | ||
GSM1146693 | Blood_Control_4 | peripheral blood | control | Uninfected | ||
GSM1146694 | Blood_PreBKV_3 | peripheral blood | pre-BKV | Uninfected | ||
GSM1146695 | Blood_BKV_10 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146696 | Blood_BKV_11 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146697 | Blood_PreBKV_4 | peripheral blood | pre-BKV | Uninfected | ||
GSM1146698 | Blood_BKV_12 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146699 | Blood_Control_5 | peripheral blood | control | Uninfected | ||
GSM1146700 | Blood_PreBKV_5 | peripheral blood | pre-BKV | Uninfected | ||
GSM1146701 | Blood_BKV_13 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146702 | Blood_BKV_14 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146703 | Blood_PreBKV_6 | peripheral blood | pre-BKV | Uninfected | ||
GSM1146704 | Blood_Control_6 | peripheral blood | control | Uninfected | ||
GSM1146705 | Blood_Control_7 | peripheral blood | control | Uninfected | ||
GSM1146706 | Blood_Control_8 | peripheral blood | control | Uninfected | ||
GSM1146707 | Blood_Control_9 | peripheral blood | control | Uninfected | ||
GSM1146708 | Blood_BKV_15 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146709 | Blood_Control_10 | peripheral blood | control | Uninfected | ||
GSM1146710 | Blood_Control_11 | peripheral blood | control | Uninfected | Data failed QCall_probeset_mad_residual_mean is 0.815043 (poor normalization, above threshold of 0.80) |
|
GSM1146711 | Blood_Control_12 | peripheral blood | control | Uninfected | ||
GSM1146712 | Blood_BKV_16 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146713 | Blood_BKV_17 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146714 | Blood_Control_13 | peripheral blood | control | Uninfected | ||
GSM1146715 | Blood_BKV_18 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146716 | Blood_PreBKV_7 | peripheral blood | pre-BKV | Uninfected | ||
GSM1146717 | Blood_Control_14 | peripheral blood | control | Uninfected | ||
GSM1146718 | Blood_BKV_19 | peripheral blood | chronic | BKV | Human polyomavirus 1 | |
GSM1146719 | Biopsy_Normal_1 | kidney | normal | Uninfected | ||
GSM1146720 | Biopsy_Normal_2 | kidney | normal | Uninfected | ||
GSM1146721 | Biopsy_BKVN_1 | kidney | chronic | BKV | Human polyomavirus 1 | Extra interventions nephropathy |
GSM1146722 | Biopsy_BKVN_2 | kidney | chronic | BKV | Human polyomavirus 1 | Extra interventions nephropathy |
GSM1146723 | Biopsy_Normal_3 | kidney | normal | Uninfected | ||
GSM1146724 | Biopsy_Normal_4 | kidney | normal | Uninfected | ||
GSM1146725 | Biopsy_Normal_5 | kidney | normal | Uninfected | ||
GSM1146726 | Biopsy_Normal_6 | kidney | normal | Uninfected | ||
GSM1146727 | Biopsy_BKVpos_1 | kidney | chronic | BKV | Human polyomavirus 1 | |
GSM1146728 | Biopsy_Normal_7 | kidney | normal | Uninfected | ||
GSM1146729 | Biopsy_Normal_8 | kidney | normal | Uninfected | ||
GSM1146730 | Biopsy_BKVN_3 | kidney | chronic | BKV | Human polyomavirus 1 | Extra interventions nephropathy |
GSM1146731 | Biopsy_Normal_9 | kidney | normal | Uninfected | ||
GSM1146732 | Biopsy_Normal_10 | kidney | normal | Uninfected | ||
GSM1146733 | Biopsy_Normal_11 | kidney | normal | Uninfected | ||
GSM1146734 | Biopsy_BKVpos_2 | kidney | chronic | BKV | Human polyomavirus 1 | |
GSM1146735 | Biopsy_BKVpos_3 | kidney | chronic | BKV | Human polyomavirus 1 |