Submitted by Jiri Zavadil (NYU SoM, USA) on Sep 17 2013
Platform: microarray – [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Pubmed: 24373965
Summary Genome-wide profiling establishes that human cytomegalovirus (HCMV) exerts an extensive, unforeseen level of specific control over which cellular mRNAs are recruited to or excluded from polyribosomes.
The landscape of translationally-regulated host mRNAs regulates HCMV replication. The HCMV imposed translational signature shares similarities with cancer cells
ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
---|---|---|---|---|---|---|
GSM1232755 | extracted total RNA, uninfected NHDFs (normal human dermal fibroblasts) rep1 | dermal fibroblast | uninfected | Uninfected | ||
GSM1232756 | extracted total RNA, uninfected NHDFs (normal human dermal fibroblasts) rep2 | dermal fibroblast | uninfected | Uninfected | ||
GSM1232757 | extracted total RNA, HCMV-infected NHDFs, 48 hr post-infection rep1 | dermal fibroblast | 48 hrs | HCMV | Human betaherpesvirus 5 | |
GSM1232758 | extracted total RNA, HCMV-infected NHDFs, 48 hr post-infection rep2 | dermal fibroblast | 48 hrs | HCMV | Human betaherpesvirus 5 | |
GSM1232759 | polysomal RNA, uninfected NHDFs rep1 | dermal fibroblast | uninfected | Uninfected | Extra interventions polysomal RNA |
|
GSM1232760 | polysomal RNA, uninfected NHDFs rep2 | dermal fibroblast | uninfected | Uninfected | Extra interventions polysomal RNA |
|
GSM1232761 | polysomal RNA, HCMV-infected NHDFs, 48 hr post-infection rep1 | dermal fibroblast | 48 hrs | HCMV | Human betaherpesvirus 5 | Extra interventions polysomal RNA |
GSM1232762 | polysomal RNA, HCMV-infected NHDFs, 48 hr post-infection rep2 | dermal fibroblast | 48 hrs | HCMV | Human betaherpesvirus 5 | Extra interventions polysomal RNA |
GSM1232763 | extracted total RNA ,uninduced NHDFs rep1 | dermal fibroblast | uninfected | Uninfected | ||
GSM1232764 | extracted total RNA, uninduced NHDFs rep2 | dermal fibroblast | uninfected | Uninfected | ||
GSM1232765 | extracted total RNA, UL38-induced, 48 hr post-induction rep1 | dermal fibroblast | uninfected | Uninfected | Extra interventions HCMV protein |
|
GSM1232766 | extracted total RNA, UL38-induced, 48 hr post-induction rep2 | dermal fibroblast | uninfected | Uninfected | Extra interventions HCMV protein |
|
GSM1232767 | polysomal RNA, uninduced NHDFs rep1 | dermal fibroblast | uninfected | Uninfected | Extra interventions polysomal RNA |
|
GSM1232768 | polysomal RNA, uninduced NHDFs rep2 | dermal fibroblast | uninfected | Uninfected | Extra interventions polysomal RNA |
|
GSM1232769 | polysomal RNA, UL38-induced NHDFs, 48 hr post-induction rep1 | dermal fibroblast | uninfected | Uninfected | Extra interventions polysomal RNA; HCMV protein |
|
GSM1232770 | polysomal RNA, UL38-induced NHDFs, 48 hr post-induction rep2 | dermal fibroblast | uninfected | Uninfected | Extra interventions polysomal RNA; HCMV protein |