Submitted by Feng Zhang (National Institutre for Food and Drug Control, China) on Dec 30 2013
Platform: microarray – [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Pubmed: 25042677
Summary Hepatitis E virus (HEV) is an important causative pathogen of acute hepatitis. Because of the absence of an in vitro culture system for HEV, research has been greatly impeded. And interaction between HEV and host cells was mainly studied by tansfection/transinfection system, such as Adeno virus transinfection system. We developed an in vitro culture system for HEV in PLC/PRF/5 cells. With this in vitro culture system, we studied the gene expression profile change by HEV infection.
Using a microarray assay, we analysed genes of PLC/PRF/5 cells, whose transcription level could be changed by HEV infection.
ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
---|---|---|---|---|---|---|
GSM1299471 | HEV inoculated PLC/PRF/5, Rep1 | hepatoma cell line [PLC/PRF/5 ] | 60 days | HEV | Orthohepevirus A | |
GSM1299472 | HEV inoculated PLC/PRF/5, Rep2 | hepatoma cell line [PLC/PRF/5 ] | 60 days | HEV | Orthohepevirus A | |
GSM1299473 | HEV inoculated PLC/PRF/5, Rep3 | hepatoma cell line [PLC/PRF/5 ] | 60 days | HEV | Orthohepevirus A | |
GSM1299474 | HEV inoculated PLC/PRF/5, Rep4 | hepatoma cell line [PLC/PRF/5 ] | 60 days | HEV | Orthohepevirus A | |
GSM1299475 | HEV inoculated PLC/PRF/5, Rep5 | hepatoma cell line [PLC/PRF/5 ] | 60 days | HEV | Orthohepevirus A | |
GSM1299476 | Control PLC/PRF/5, Rep1 | hepatoma cell line [PLC/PRF/5 ] | 60 days | control | Uninfected | |
GSM1299477 | Control PLC/PRF/5, Rep2 | hepatoma cell line [PLC/PRF/5 ] | 60 days | control | Uninfected | |
GSM1299478 | Control PLC/PRF/5, Rep3 | hepatoma cell line [PLC/PRF/5 ] | 60 days | control | Uninfected | |
GSM1299479 | Control PLC/PRF/5, Rep4 | hepatoma cell line [PLC/PRF/5 ] | 60 days | control | Uninfected | |
GSM1299480 | Control PLC/PRF/5, Rep5 | hepatoma cell line [PLC/PRF/5 ] | 60 days | control | Uninfected |