Virus Expression Database
Submitted by Adriano Boasso (Imperial College London, United Kingdom) on Jul 01 2014
Platform: microarray – [HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version]
Pubmed: 25156368
Summary HIV-1 and HIV-2 can both infect humans, but HIV-2 causes a slow progressing disease and is well controlled by the immune system for prolonged period of times.
Here we tested acute response aainst HIV-1 and HIV-2 exposure in peripheral blood mononuclear cells (PBMC) from three indepednent donors.
| ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
|---|---|---|---|---|---|---|
| GSM1423557 | PBMC from Donor A at 6h in Media | peripheral blood mononuclear cell  |
6 hrs | media | Uninfected | |
| GSM1423558 | PBMC from Donor A at 6h with HIV-1 | peripheral blood mononuclear cell |
6 hrs | HIV-1 | Human immunodeficiency virus 1 | |
| GSM1423559 | PBMC from Donor A at 6h with HIV-2 | peripheral blood mononuclear cell |
6 hrs | HIV-2 | Human immunodeficiency virus 2 | |
| GSM1423560 | PBMC from Donor A at 6h with CpG-A | peripheral blood mononuclear cell |
6 hrs | CpG-A | Uninfected | Extra interventions CpG-A is a TLR-9 agonist |
| GSM1423561 | PBMC from Donor B at 6h in Media | peripheral blood mononuclear cell |
6 hrs | media | Uninfected | |
| GSM1423562 | PBMC from Donor B at 6h with HIV-1 | peripheral blood mononuclear cell |
6 hrs | HIV-1 | Human immunodeficiency virus 1 | |
| GSM1423563 | PBMC from Donor B at 6h with HIV-2 | peripheral blood mononuclear cell |
6 hrs | HIV-2 | Human immunodeficiency virus 2 | |
| GSM1423564 | PBMC from Donor B at 6h with CpG-A | peripheral blood mononuclear cell |
6 hrs | CpG-A | Uninfected | Extra interventions CpG-A is a TLR-9 agonist |
| GSM1423565 | PBMC from Donor C at 6h in Media | peripheral blood mononuclear cell |
6 hrs | media | Uninfected | |
| GSM1423566 | PBMC from Donor C at 6h with HIV-1 | peripheral blood mononuclear cell |
6 hrs | HIV-1 | Human immunodeficiency virus 1 | |
| GSM1423567 | PBMC from Donor C at 6h with HIV-2 | peripheral blood mononuclear cell |
6 hrs | HIV-2 | Human immunodeficiency virus 2 | |
| GSM1423568 | PBMC from Donor C at 6h with CpG-A | peripheral blood mononuclear cell |
6 hrs | CpG-A | Uninfected | Extra interventions CpG-A is a TLR-9 agonist |
| GSM1423569 | PBMC from Donor A at 12h in Media | peripheral blood mononuclear cell |
12 hrs | media | Uninfected | |
| GSM1423570 | PBMC from Donor A at 12h with HIV-1 | peripheral blood mononuclear cell |
12 hrs | HIV-1 | Human immunodeficiency virus 1 | |
| GSM1423571 | PBMC from Donor A at 12h with HIV-2 | peripheral blood mononuclear cell |
12 hrs | HIV-2 | Human immunodeficiency virus 2 | |
| GSM1423572 | PBMC from Donor A at 12h with CpG-A | peripheral blood mononuclear cell |
12 hrs | CpG-A | Uninfected | Extra interventions CpG-A is a TLR-9 agonist |
| GSM1423573 | PBMC from Donor B at 12h in Media | peripheral blood mononuclear cell |
12 hrs | media | Uninfected | |
| GSM1423574 | PBMC from Donor B at 12h with HIV-1 | peripheral blood mononuclear cell |
12 hrs | HIV-1 | Human immunodeficiency virus 1 | |
| GSM1423575 | PBMC from Donor B at 12h with HIV-2 | peripheral blood mononuclear cell |
12 hrs | HIV-2 | Human immunodeficiency virus 2 | |
| GSM1423576 | PBMC from Donor B at 12h with CpG-A | peripheral blood mononuclear cell |
12 hrs | CpG-A | Uninfected | Extra interventions CpG-A is a TLR-9 agonist |
| GSM1423577 | PBMC from Donor C at 12h in Media | peripheral blood mononuclear cell |
12 hrs | media | Uninfected | |
| GSM1423578 | PBMC from Donor C at 12h with HIV-1 | peripheral blood mononuclear cell |
12 hrs | HIV-1 | Human immunodeficiency virus 1 | |
| GSM1423579 | PBMC from Donor C at 12h with HIV-2 | peripheral blood mononuclear cell |
12 hrs | HIV-2 | Human immunodeficiency virus 2 | |
| GSM1423580 | PBMC from Donor C at 12h with CpG-A | peripheral blood mononuclear cell |
12 hrs | CpG-A | Uninfected | Extra interventions CpG-A is a TLR-9 agonist |