Virus Expression Database

GSE71766

A Systems Approach to Understanding Human Rhinovirus and Influenza Virus Infection

Submitted by Richard Gelinas (Institute for Systems Biology, USA) on Aug 05 2015

Platform: microarray – [HG-U219] Affymetrix Human Genome U219 Array

Pubmed: 26437235

Summary Human rhinovirus and influenza virus infections of the upper airway lead to colds and the flu and can trigger exacerbations of lower airway diseases including asthma and chronic obstructive pulmonary disease. Despite modest advances in the diagnosis and treatment of infections by these viruses, novel diagnostic and therapeutic targets are still needed to differentiate between the cold and the flu, since the clinical course of influenza can be severe while that of rhinovirus is usually more mild.
In our investigation of influenza and rhinovirus infection of human respiratory epithelial cells, we used a systems approach to identify the temporally changing patterns of host gene expression from these viruses. After infection of human bronchial epithelial cells (BEAS-2B) with rhinovirus, influenza virus or co-infection with both viruses, we studied the time-course of host gene expression changes over three days. From these data, we constructed a transcriptional regulatory network model that revealed shared and unique host responses to these viral infections such that after a lag of 4-8 hours, most cell host responses were similar for both viruses, while divergent host cell responses appeared after 24-48 hours. The similarities and differences in gene expression after epithelial infection of rhinovirus, influenza virus, or both viruses together revealed qualitative and quantitative differences in innate immune activation and regulation. These differences help explain the generally mild outcome of rhinovirus infections compared to influenza infections which can be much more severe.

186 Samples

ID Title Cell Type Timepoint Reported Virus Virus Species Exclusion Reason
GSM1844791 BEAS-2B, control baseline, Biological replicate1 bronchial epithelial cell  control Uninfected
GSM1844792 BEAS-2B, control baseline, Biological replicate2 bronchial epithelial cell  control Uninfected
GSM1844793 BEAS-2B, control baseline, Biological replicate3 bronchial epithelial cell  control Uninfected
GSM1844794 BEAS-2B, control baseline, Biological replicate4 bronchial epithelial cell  control Uninfected
GSM1844795 BEAS-2B, control baseline, Biological replicate5 bronchial epithelial cell  control Uninfected
GSM1844796 BEAS-2B, control baseline, Biological replicate6 bronchial epithelial cell  control Uninfected
GSM1844797 BEAS-2B, control 2hrs, Biological replicate1 bronchial epithelial cell  2 hrs control Uninfected
GSM1844798 BEAS-2B, control 2hrs, Biological replicate2 bronchial epithelial cell  2 hrs control Uninfected
GSM1844799 BEAS-2B, control 2hrs, Biological replicate3 bronchial epithelial cell  2 hrs control Uninfected
GSM1844800 BEAS-2B, control 2hrs, Biological replicate4 bronchial epithelial cell  2 hrs control Uninfected
GSM1844801 BEAS-2B, control 2hrs, Biological replicate5 bronchial epithelial cell  2 hrs control Uninfected
GSM1844802 BEAS-2B, control 4hrs, Biological replicate1 bronchial epithelial cell  4 hrs control Uninfected
GSM1844803 BEAS-2B, control 4hrs, Biological replicate2 bronchial epithelial cell  4 hrs control Uninfected
GSM1844804 BEAS-2B, control 4hrs, Biological replicate3 bronchial epithelial cell  4 hrs control Uninfected
GSM1844805 BEAS-2B, control 4hrs, Biological replicate4 bronchial epithelial cell  4 hrs control Uninfected
GSM1844806 BEAS-2B, control 4hrs, Biological replicate5 bronchial epithelial cell  4 hrs control Uninfected
GSM1844807 BEAS-2B, control 8hrs, Biological replicate1 bronchial epithelial cell  8 hrs control Uninfected
GSM1844808 BEAS-2B, control 8hrs, Biological replicate2 bronchial epithelial cell  8 hrs control Uninfected
GSM1844809 BEAS-2B, control 8hrs, Biological replicate3 bronchial epithelial cell  8 hrs control Uninfected
GSM1844810 BEAS-2B, control 8hrs, Biological replicate4 bronchial epithelial cell  8 hrs control Uninfected
GSM1844811 BEAS-2B, control 8hrs, Biological replicate5 bronchial epithelial cell  8 hrs control Uninfected
GSM1844812 BEAS-2B, control 12hrs, Biological replicate1 bronchial epithelial cell  12 hrs control Uninfected
GSM1844813 BEAS-2B, control 12hrs, Biological replicate2 bronchial epithelial cell  12 hrs control Uninfected
GSM1844814 BEAS-2B, control 12hrs, Biological replicate3 bronchial epithelial cell  12 hrs control Uninfected
GSM1844815 BEAS-2B, control 12hrs, Biological replicate4 bronchial epithelial cell  12 hrs control Uninfected
GSM1844816 BEAS-2B, control 12hrs, Biological replicate5 bronchial epithelial cell  12 hrs control Uninfected
GSM1844817 BEAS-2B, control 24hrs, Biological replicate1 bronchial epithelial cell  24 hrs control Uninfected
GSM1844818 BEAS-2B, control 24hrs, Biological replicate2 bronchial epithelial cell  24 hrs control Uninfected
GSM1844819 BEAS-2B, control 24hrs, Biological replicate3 bronchial epithelial cell  24 hrs control Uninfected
GSM1844820 BEAS-2B, control 24hrs, Biological replicate4 bronchial epithelial cell  24 hrs control Uninfected
GSM1844821 BEAS-2B, control 24hrs, Biological replicate5 bronchial epithelial cell  24 hrs control Uninfected
GSM1844822 BEAS-2B, control 36hrs, Biological replicate1 bronchial epithelial cell  36 hrs control Uninfected
GSM1844823 BEAS-2B, control 36hrs, Biological replicate2 bronchial epithelial cell  36 hrs control Uninfected
GSM1844824 BEAS-2B, control 36hrs, Biological replicate3 bronchial epithelial cell  36 hrs control Uninfected
GSM1844825 BEAS-2B, control 36hrs, Biological replicate4 bronchial epithelial cell  36 hrs control Uninfected
GSM1844826 BEAS-2B, control 36hrs, Biological replicate5 bronchial epithelial cell  36 hrs control Uninfected
GSM1844827 BEAS-2B, control 48hrs, Biological replicate1 bronchial epithelial cell  48 hrs control Uninfected
GSM1844828 BEAS-2B, control 48hrs, Biological replicate2 bronchial epithelial cell  48 hrs control Uninfected
GSM1844829 BEAS-2B, control 48hrs, Biological replicate3 bronchial epithelial cell  48 hrs control Uninfected
GSM1844830 BEAS-2B, control 48hrs, Biological replicate4 bronchial epithelial cell  48 hrs control Uninfected
GSM1844831 BEAS-2B, control 48hrs, Biological replicate5 bronchial epithelial cell  48 hrs control Uninfected
GSM1844832 BEAS-2B, control 60hrs, Biological replicate1 bronchial epithelial cell  60 hrs control Uninfected
GSM1844833 BEAS-2B, control 60hrs, Biological replicate2 bronchial epithelial cell  60 hrs control Uninfected
GSM1844834 BEAS-2B, control 60hrs, Biological replicate3 bronchial epithelial cell  60 hrs control Uninfected
GSM1844835 BEAS-2B, control 60hrs, Biological replicate4 bronchial epithelial cell  60 hrs control Uninfected
GSM1844836 BEAS-2B, control 60hrs, Biological replicate5 bronchial epithelial cell  60 hrs control Uninfected
GSM1844837 BEAS-2B, control 72hrs, Biological replicate1 bronchial epithelial cell  72 hrs control Uninfected
GSM1844838 BEAS-2B, control 72hrs, Biological replicate2 bronchial epithelial cell  72 hrs control Uninfected
GSM1844839 BEAS-2B, control 72hrs, Biological replicate3 bronchial epithelial cell  72 hrs control Uninfected
GSM1844840 BEAS-2B, control 72hrs, Biological replicate4 bronchial epithelial cell  72 hrs control Uninfected
GSM1844841 BEAS-2B, control 72hrs, Biological replicate5 bronchial epithelial cell  72 hrs control Uninfected
GSM1844842 BEAS-2B, InfluenzaVirus 2hrs, Biological replicate1 bronchial epithelial cell  2 hrs InfluenzaVirus Influenza A virus
GSM1844843 BEAS-2B, InfluenzaVirus 2hrs, Biological replicate2 bronchial epithelial cell  2 hrs InfluenzaVirus Influenza A virus
GSM1844844 BEAS-2B, InfluenzaVirus 2hrs, Biological replicate3 bronchial epithelial cell  2 hrs InfluenzaVirus Influenza A virus
GSM1844845 BEAS-2B, InfluenzaVirus 2hrs, Biological replicate4 bronchial epithelial cell  2 hrs InfluenzaVirus Influenza A virus
GSM1844846 BEAS-2B, InfluenzaVirus 2hrs, Biological replicate5 bronchial epithelial cell  2 hrs InfluenzaVirus Influenza A virus
GSM1844847 BEAS-2B, InfluenzaVirus 4hrs, Biological replicate1 bronchial epithelial cell  4 hrs InfluenzaVirus Influenza A virus
GSM1844848 BEAS-2B, InfluenzaVirus 4hrs, Biological replicate2 bronchial epithelial cell  4 hrs InfluenzaVirus Influenza A virus
GSM1844849 BEAS-2B, InfluenzaVirus 4hrs, Biological replicate3 bronchial epithelial cell  4 hrs InfluenzaVirus Influenza A virus
GSM1844850 BEAS-2B, InfluenzaVirus 4hrs, Biological replicate4 bronchial epithelial cell  4 hrs InfluenzaVirus Influenza A virus
GSM1844851 BEAS-2B, InfluenzaVirus 4hrs, Biological replicate5 bronchial epithelial cell  4 hrs InfluenzaVirus Influenza A virus
GSM1844852 BEAS-2B, InfluenzaVirus 8hrs, Biological replicate1 bronchial epithelial cell  8 hrs InfluenzaVirus Influenza A virus
GSM1844853 BEAS-2B, InfluenzaVirus 8hrs, Biological replicate2 bronchial epithelial cell  8 hrs InfluenzaVirus Influenza A virus
GSM1844854 BEAS-2B, InfluenzaVirus 8hrs, Biological replicate3 bronchial epithelial cell  8 hrs InfluenzaVirus Influenza A virus
GSM1844855 BEAS-2B, InfluenzaVirus 8hrs, Biological replicate4 bronchial epithelial cell  8 hrs InfluenzaVirus Influenza A virus
GSM1844856 BEAS-2B, InfluenzaVirus 8hrs, Biological replicate5 bronchial epithelial cell  8 hrs InfluenzaVirus Influenza A virus
GSM1844857 BEAS-2B, InfluenzaVirus 12hrs, Biological replicate1 bronchial epithelial cell  12 hrs InfluenzaVirus Influenza A virus
GSM1844858 BEAS-2B, InfluenzaVirus 12hrs, Biological replicate2 bronchial epithelial cell  12 hrs InfluenzaVirus Influenza A virus
GSM1844859 BEAS-2B, InfluenzaVirus 12hrs, Biological replicate3 bronchial epithelial cell  12 hrs InfluenzaVirus Influenza A virus
GSM1844860 BEAS-2B, InfluenzaVirus 12hrs, Biological replicate4 bronchial epithelial cell  12 hrs InfluenzaVirus Influenza A virus
GSM1844861 BEAS-2B, InfluenzaVirus 12hrs, Biological replicate5 bronchial epithelial cell  12 hrs InfluenzaVirus Influenza A virus
GSM1844862 BEAS-2B, InfluenzaVirus 24hrs, Biological replicate1 bronchial epithelial cell  24 hrs InfluenzaVirus Influenza A virus
GSM1844863 BEAS-2B, InfluenzaVirus 24hrs, Biological replicate2 bronchial epithelial cell  24 hrs InfluenzaVirus Influenza A virus
GSM1844864 BEAS-2B, InfluenzaVirus 24hrs, Biological replicate3 bronchial epithelial cell  24 hrs InfluenzaVirus Influenza A virus
GSM1844865 BEAS-2B, InfluenzaVirus 24hrs, Biological replicate4 bronchial epithelial cell  24 hrs InfluenzaVirus Influenza A virus
GSM1844866 BEAS-2B, InfluenzaVirus 24hrs, Biological replicate5 bronchial epithelial cell  24 hrs InfluenzaVirus Influenza A virus
GSM1844867 BEAS-2B, InfluenzaVirus 36hrs, Biological replicate1 bronchial epithelial cell  36 hrs InfluenzaVirus Influenza A virus
GSM1844868 BEAS-2B, InfluenzaVirus 36hrs, Biological replicate2 bronchial epithelial cell  36 hrs InfluenzaVirus Influenza A virus
GSM1844869 BEAS-2B, InfluenzaVirus 36hrs, Biological replicate3 bronchial epithelial cell  36 hrs InfluenzaVirus Influenza A virus
GSM1844870 BEAS-2B, InfluenzaVirus 36hrs, Biological replicate4 bronchial epithelial cell  36 hrs InfluenzaVirus Influenza A virus
GSM1844871 BEAS-2B, InfluenzaVirus 36hrs, Biological replicate5 bronchial epithelial cell  36 hrs InfluenzaVirus Influenza A virus
GSM1844872 BEAS-2B, InfluenzaVirus 48hrs, Biological replicate1 bronchial epithelial cell  48 hrs InfluenzaVirus Influenza A virus
GSM1844873 BEAS-2B, InfluenzaVirus 48hrs, Biological replicate2 bronchial epithelial cell  48 hrs InfluenzaVirus Influenza A virus
GSM1844874 BEAS-2B, InfluenzaVirus 48hrs, Biological replicate3 bronchial epithelial cell  48 hrs InfluenzaVirus Influenza A virus
GSM1844875 BEAS-2B, InfluenzaVirus 48hrs, Biological replicate4 bronchial epithelial cell  48 hrs InfluenzaVirus Influenza A virus
GSM1844876 BEAS-2B, InfluenzaVirus 48hrs, Biological replicate5 bronchial epithelial cell  48 hrs InfluenzaVirus Influenza A virus
GSM1844877 BEAS-2B, InfluenzaVirus 60hrs, Biological replicate1 bronchial epithelial cell  60 hrs InfluenzaVirus Influenza A virus
GSM1844878 BEAS-2B, InfluenzaVirus 60hrs, Biological replicate2 bronchial epithelial cell  60 hrs InfluenzaVirus Influenza A virus
GSM1844879 BEAS-2B, InfluenzaVirus 60hrs, Biological replicate3 bronchial epithelial cell  60 hrs InfluenzaVirus Influenza A virus
GSM1844880 BEAS-2B, InfluenzaVirus 60hrs, Biological replicate4 bronchial epithelial cell  60 hrs InfluenzaVirus Influenza A virus
GSM1844881 BEAS-2B, InfluenzaVirus 60hrs, Biological replicate5 bronchial epithelial cell  60 hrs InfluenzaVirus Influenza A virus
GSM1844882 BEAS-2B, InfluenzaVirus 72hrs, Biological replicate1 bronchial epithelial cell  72 hrs InfluenzaVirus Influenza A virus
GSM1844883 BEAS-2B, InfluenzaVirus 72hrs, Biological replicate2 bronchial epithelial cell  72 hrs InfluenzaVirus Influenza A virus
GSM1844884 BEAS-2B, InfluenzaVirus 72hrs, Biological replicate3 bronchial epithelial cell  72 hrs InfluenzaVirus Influenza A virus
GSM1844885 BEAS-2B, InfluenzaVirus 72hrs, Biological replicate4 bronchial epithelial cell  72 hrs InfluenzaVirus Influenza A virus
GSM1844886 BEAS-2B, InfluenzaVirus 72hrs, Biological replicate5 bronchial epithelial cell  72 hrs InfluenzaVirus Influenza A virus
GSM1844887 BEAS-2B, RhinoVirus 2hrs, Biological replicate1 bronchial epithelial cell  2 hrs RhinoVirus Rhinovirus A
GSM1844888 BEAS-2B, RhinoVirus 2hrs, Biological replicate2 bronchial epithelial cell  2 hrs RhinoVirus Rhinovirus A
GSM1844889 BEAS-2B, RhinoVirus 2hrs, Biological replicate3 bronchial epithelial cell  2 hrs RhinoVirus Rhinovirus A
GSM1844890 BEAS-2B, RhinoVirus 2hrs, Biological replicate4 bronchial epithelial cell  2 hrs RhinoVirus Rhinovirus A
GSM1844891 BEAS-2B, RhinoVirus 2hrs, Biological replicate5 bronchial epithelial cell  2 hrs RhinoVirus Rhinovirus A
GSM1844892 BEAS-2B, RhinoVirus 4hrs, Biological replicate1 bronchial epithelial cell  4 hrs RhinoVirus Rhinovirus A
GSM1844893 BEAS-2B, RhinoVirus 4hrs, Biological replicate2 bronchial epithelial cell  4 hrs RhinoVirus Rhinovirus A
GSM1844894 BEAS-2B, RhinoVirus 4hrs, Biological replicate3 bronchial epithelial cell  4 hrs RhinoVirus Rhinovirus A
GSM1844895 BEAS-2B, RhinoVirus 4hrs, Biological replicate4 bronchial epithelial cell  4 hrs RhinoVirus Rhinovirus A
GSM1844896 BEAS-2B, RhinoVirus 4hrs, Biological replicate5 bronchial epithelial cell  4 hrs RhinoVirus Rhinovirus A
GSM1844897 BEAS-2B, RhinoVirus 8hrs, Biological replicate1 bronchial epithelial cell  8 hrs RhinoVirus Rhinovirus A
GSM1844898 BEAS-2B, RhinoVirus 8hrs, Biological replicate2 bronchial epithelial cell  8 hrs RhinoVirus Rhinovirus A
GSM1844899 BEAS-2B, RhinoVirus 8hrs, Biological replicate3 bronchial epithelial cell  8 hrs RhinoVirus Rhinovirus A
GSM1844900 BEAS-2B, RhinoVirus 8hrs, Biological replicate4 bronchial epithelial cell  8 hrs RhinoVirus Rhinovirus A
GSM1844901 BEAS-2B, RhinoVirus 8hrs, Biological replicate5 bronchial epithelial cell  8 hrs RhinoVirus Rhinovirus A
GSM1844902 BEAS-2B, RhinoVirus 12hrs, Biological replicate1 bronchial epithelial cell  12 hrs RhinoVirus Rhinovirus A
GSM1844903 BEAS-2B, RhinoVirus 12hrs, Biological replicate2 bronchial epithelial cell  12 hrs RhinoVirus Rhinovirus A
GSM1844904 BEAS-2B, RhinoVirus 12hrs, Biological replicate3 bronchial epithelial cell  12 hrs RhinoVirus Rhinovirus A
GSM1844905 BEAS-2B, RhinoVirus 12hrs, Biological replicate4 bronchial epithelial cell  12 hrs RhinoVirus Rhinovirus A
GSM1844906 BEAS-2B, RhinoVirus 12hrs, Biological replicate5 bronchial epithelial cell  12 hrs RhinoVirus Rhinovirus A
GSM1844907 BEAS-2B, RhinoVirus 24hrs, Biological replicate1 bronchial epithelial cell  24 hrs RhinoVirus Rhinovirus A
GSM1844908 BEAS-2B, RhinoVirus 24hrs, Biological replicate2 bronchial epithelial cell  24 hrs RhinoVirus Rhinovirus A
GSM1844909 BEAS-2B, RhinoVirus 24hrs, Biological replicate3 bronchial epithelial cell  24 hrs RhinoVirus Rhinovirus A
GSM1844910 BEAS-2B, RhinoVirus 24hrs, Biological replicate4 bronchial epithelial cell  24 hrs RhinoVirus Rhinovirus A
GSM1844911 BEAS-2B, RhinoVirus 24hrs, Biological replicate5 bronchial epithelial cell  24 hrs RhinoVirus Rhinovirus A
GSM1844912 BEAS-2B, RhinoVirus 36hrs, Biological replicate1 bronchial epithelial cell  36 hrs RhinoVirus Rhinovirus A
GSM1844913 BEAS-2B, RhinoVirus 36hrs, Biological replicate2 bronchial epithelial cell  36 hrs RhinoVirus Rhinovirus A
GSM1844914 BEAS-2B, RhinoVirus 36hrs, Biological replicate3 bronchial epithelial cell  36 hrs RhinoVirus Rhinovirus A
GSM1844915 BEAS-2B, RhinoVirus 36hrs, Biological replicate4 bronchial epithelial cell  36 hrs RhinoVirus Rhinovirus A
GSM1844916 BEAS-2B, RhinoVirus 36hrs, Biological replicate5 bronchial epithelial cell  36 hrs RhinoVirus Rhinovirus A
GSM1844917 BEAS-2B, RhinoVirus 48hrs, Biological replicate1 bronchial epithelial cell  48 hrs RhinoVirus Rhinovirus A
GSM1844918 BEAS-2B, RhinoVirus 48hrs, Biological replicate2 bronchial epithelial cell  48 hrs RhinoVirus Rhinovirus A
GSM1844919 BEAS-2B, RhinoVirus 48hrs, Biological replicate3 bronchial epithelial cell  48 hrs RhinoVirus Rhinovirus A
GSM1844920 BEAS-2B, RhinoVirus 48hrs, Biological replicate4 bronchial epithelial cell  48 hrs RhinoVirus Rhinovirus A
GSM1844921 BEAS-2B, RhinoVirus 48hrs, Biological replicate5 bronchial epithelial cell  48 hrs RhinoVirus Rhinovirus A
GSM1844922 BEAS-2B, RhinoVirus 60hrs, Biological replicate1 bronchial epithelial cell  60 hrs RhinoVirus Rhinovirus A
GSM1844923 BEAS-2B, RhinoVirus 60hrs, Biological replicate2 bronchial epithelial cell  60 hrs RhinoVirus Rhinovirus A
GSM1844924 BEAS-2B, RhinoVirus 60hrs, Biological replicate3 bronchial epithelial cell  60 hrs RhinoVirus Rhinovirus A
GSM1844925 BEAS-2B, RhinoVirus 60hrs, Biological replicate4 bronchial epithelial cell  60 hrs RhinoVirus Rhinovirus A
GSM1844926 BEAS-2B, RhinoVirus 60hrs, Biological replicate5 bronchial epithelial cell  60 hrs RhinoVirus Rhinovirus A
GSM1844927 BEAS-2B, RhinoVirus 72hrs, Biological replicate1 bronchial epithelial cell  72 hrs RhinoVirus Rhinovirus A
GSM1844928 BEAS-2B, RhinoVirus 72hrs, Biological replicate2 bronchial epithelial cell  72 hrs RhinoVirus Rhinovirus A
GSM1844929 BEAS-2B, RhinoVirus 72hrs, Biological replicate3 bronchial epithelial cell  72 hrs RhinoVirus Rhinovirus A
GSM1844930 BEAS-2B, RhinoVirus 72hrs, Biological replicate4 bronchial epithelial cell  72 hrs RhinoVirus Rhinovirus A
GSM1844931 BEAS-2B, RhinoVirus 72hrs, Biological replicate5 bronchial epithelial cell  72 hrs RhinoVirus Rhinovirus A
GSM1844932 BEAS-2B, Both InfluenzaVirus and RhinoVirus 2hrs, Biological replicate1 bronchial epithelial cell  2 hrs Coinfection
GSM1844933 BEAS-2B, Both InfluenzaVirus and RhinoVirus 2hrs, Biological replicate2 bronchial epithelial cell  2 hrs Coinfection
GSM1844934 BEAS-2B, Both InfluenzaVirus and RhinoVirus 2hrs, Biological replicate3 bronchial epithelial cell  2 hrs Coinfection
GSM1844935 BEAS-2B, Both InfluenzaVirus and RhinoVirus 2hrs, Biological replicate4 bronchial epithelial cell  2 hrs Coinfection
GSM1844936 BEAS-2B, Both InfluenzaVirus and RhinoVirus 2hrs, Biological replicate5 bronchial epithelial cell  2 hrs Coinfection
GSM1844937 BEAS-2B, Both InfluenzaVirus and RhinoVirus 4hrs, Biological replicate1 bronchial epithelial cell  4 hrs Coinfection
GSM1844938 BEAS-2B, Both InfluenzaVirus and RhinoVirus 4hrs, Biological replicate2 bronchial epithelial cell  4 hrs Coinfection
GSM1844939 BEAS-2B, Both InfluenzaVirus and RhinoVirus 4hrs, Biological replicate3 bronchial epithelial cell  4 hrs Coinfection
GSM1844940 BEAS-2B, Both InfluenzaVirus and RhinoVirus 4hrs, Biological replicate4 bronchial epithelial cell  4 hrs Coinfection
GSM1844941 BEAS-2B, Both InfluenzaVirus and RhinoVirus 4hrs, Biological replicate5 bronchial epithelial cell  4 hrs Coinfection
GSM1844942 BEAS-2B, Both InfluenzaVirus and RhinoVirus 8hrs, Biological replicate1 bronchial epithelial cell  8 hrs Coinfection
GSM1844943 BEAS-2B, Both InfluenzaVirus and RhinoVirus 8hrs, Biological replicate2 bronchial epithelial cell  8 hrs Coinfection
GSM1844944 BEAS-2B, Both InfluenzaVirus and RhinoVirus 8hrs, Biological replicate3 bronchial epithelial cell  8 hrs Coinfection
GSM1844945 BEAS-2B, Both InfluenzaVirus and RhinoVirus 8hrs, Biological replicate4 bronchial epithelial cell  8 hrs Coinfection
GSM1844946 BEAS-2B, Both InfluenzaVirus and RhinoVirus 8hrs, Biological replicate5 bronchial epithelial cell  8 hrs Coinfection
GSM1844947 BEAS-2B, Both InfluenzaVirus and RhinoVirus 12hrs, Biological replicate1 bronchial epithelial cell  12 hrs Coinfection
GSM1844948 BEAS-2B, Both InfluenzaVirus and RhinoVirus 12hrs, Biological replicate2 bronchial epithelial cell  12 hrs Coinfection
GSM1844949 BEAS-2B, Both InfluenzaVirus and RhinoVirus 12hrs, Biological replicate3 bronchial epithelial cell  12 hrs Coinfection
GSM1844950 BEAS-2B, Both InfluenzaVirus and RhinoVirus 12hrs, Biological replicate4 bronchial epithelial cell  12 hrs Coinfection
GSM1844951 BEAS-2B, Both InfluenzaVirus and RhinoVirus 12hrs, Biological replicate5 bronchial epithelial cell  12 hrs Coinfection
GSM1844952 BEAS-2B, Both InfluenzaVirus and RhinoVirus 24hrs, Biological replicate1 bronchial epithelial cell  24 hrs Coinfection
GSM1844953 BEAS-2B, Both InfluenzaVirus and RhinoVirus 24hrs, Biological replicate2 bronchial epithelial cell  24 hrs Coinfection
GSM1844954 BEAS-2B, Both InfluenzaVirus and RhinoVirus 24hrs, Biological replicate3 bronchial epithelial cell  24 hrs Coinfection
GSM1844955 BEAS-2B, Both InfluenzaVirus and RhinoVirus 24hrs, Biological replicate4 bronchial epithelial cell  24 hrs Coinfection
GSM1844956 BEAS-2B, Both InfluenzaVirus and RhinoVirus 24hrs, Biological replicate5 bronchial epithelial cell  24 hrs Coinfection
GSM1844957 BEAS-2B, Both InfluenzaVirus and RhinoVirus 36hrs, Biological replicate1 bronchial epithelial cell  36 hrs Coinfection
GSM1844958 BEAS-2B, Both InfluenzaVirus and RhinoVirus 36hrs, Biological replicate2 bronchial epithelial cell  36 hrs Coinfection
GSM1844959 BEAS-2B, Both InfluenzaVirus and RhinoVirus 36hrs, Biological replicate3 bronchial epithelial cell  36 hrs Coinfection
GSM1844960 BEAS-2B, Both InfluenzaVirus and RhinoVirus 36hrs, Biological replicate4 bronchial epithelial cell  36 hrs Coinfection
GSM1844961 BEAS-2B, Both InfluenzaVirus and RhinoVirus 36hrs, Biological replicate5 bronchial epithelial cell  36 hrs Coinfection
GSM1844962 BEAS-2B, Both InfluenzaVirus and RhinoVirus 48hrs, Biological replicate1 bronchial epithelial cell  48 hrs Coinfection
GSM1844963 BEAS-2B, Both InfluenzaVirus and RhinoVirus 48hrs, Biological replicate2 bronchial epithelial cell  48 hrs Coinfection
GSM1844964 BEAS-2B, Both InfluenzaVirus and RhinoVirus 48hrs, Biological replicate3 bronchial epithelial cell  48 hrs Coinfection
GSM1844965 BEAS-2B, Both InfluenzaVirus and RhinoVirus 48hrs, Biological replicate4 bronchial epithelial cell  48 hrs Coinfection
GSM1844966 BEAS-2B, Both InfluenzaVirus and RhinoVirus 48hrs, Biological replicate5 bronchial epithelial cell  48 hrs Coinfection
GSM1844967 BEAS-2B, Both InfluenzaVirus and RhinoVirus 60hrs, Biological replicate1 bronchial epithelial cell  60 hrs Coinfection
GSM1844968 BEAS-2B, Both InfluenzaVirus and RhinoVirus 60hrs, Biological replicate2 bronchial epithelial cell  60 hrs Coinfection
GSM1844969 BEAS-2B, Both InfluenzaVirus and RhinoVirus 60hrs, Biological replicate3 bronchial epithelial cell  60 hrs Coinfection
GSM1844970 BEAS-2B, Both InfluenzaVirus and RhinoVirus 60hrs, Biological replicate4 bronchial epithelial cell  60 hrs Coinfection
GSM1844971 BEAS-2B, Both InfluenzaVirus and RhinoVirus 60hrs, Biological replicate5 bronchial epithelial cell  60 hrs Coinfection
GSM1844972 BEAS-2B, Both InfluenzaVirus and RhinoVirus 72hrs, Biological replicate1 bronchial epithelial cell  72 hrs Coinfection
GSM1844973 BEAS-2B, Both InfluenzaVirus and RhinoVirus 72hrs, Biological replicate2 bronchial epithelial cell  72 hrs Coinfection
GSM1844974 BEAS-2B, Both InfluenzaVirus and RhinoVirus 72hrs, Biological replicate3 bronchial epithelial cell  72 hrs Coinfection
GSM1844975 BEAS-2B, Both InfluenzaVirus and RhinoVirus 72hrs, Biological replicate4 bronchial epithelial cell  72 hrs Coinfection
GSM1844976 BEAS-2B, Both InfluenzaVirus and RhinoVirus 72hrs, Biological replicate5 bronchial epithelial cell  72 hrs Coinfection