Virus Expression Database
Submitted by Karyn Mcfadden (Duke, USA) on Dec 18 2015
Platform: microarray – [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Pubmed: 26802124
Summary Early after infection, Epstein-Barr Virus (EBV) induces a transient period of hyper-proliferation that is suppressed by the activation of the DNA damage response and a G1/S phase growth arrest. This growth arrest prevents long-term outgrowth of the majority of infected cells. We developed a method to isolate and characterize infected cells that arrest after this early burst of proliferation.
We used microarray analysis to uncover changes in gene expression that could give us a better understanding of the pathways that attenuate immortalization.
| ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
|---|---|---|---|---|---|---|
| GSM1974933 | PP, biological replicate 1 | peripheral blood mononuclear cell  |
7.5 days | EBV B95-8 | Human gammaherpesvirus 4 | |
| GSM1974934 | PA, biological replicate 1 | peripheral blood mononuclear cell |
7.5 days | EBV B95-8 | Human gammaherpesvirus 4 | |
| GSM1974935 | PP, biological replicate 2 | peripheral blood mononuclear cell |
7.5 days | EBV B95-8 | Human gammaherpesvirus 4 | |
| GSM1974936 | PA, biological replicate 2 | peripheral blood mononuclear cell |
7.5 days | EBV B95-8 | Human gammaherpesvirus 4 | |
| GSM1974937 | PP, biological replicate 3 | peripheral blood mononuclear cell |
7.5 days | EBV B95-8 | Human gammaherpesvirus 4 | |
| GSM1974938 | PA, biological replicate 3 | peripheral blood mononuclear cell |
7.5 days | EBV B95-8 | Human gammaherpesvirus 4 |