Submitted by Akul Singhania (The Francis Crick Institute, United Kingdom) on Jan 22 2016
Platform: microarray – [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Pubmed: 28481620
Summary This in-vitro study suggests the inflammatory environment of naive epithelial cells can induce epigenetic modulation of innate immune responses at the level of histone methylation and potentially lead to long-term impacts on anti-viral immunity.
ID | Title | Cell Type | Timepoint | Reported Virus | Virus Species | Exclusion Reason |
---|---|---|---|---|---|---|
GSM2044944 | Control sample, rep 1 | bronchial epithelial cell line [AALEB ] | none | Uninfected | ||
GSM2044945 | Control sample, rep 2 | bronchial epithelial cell line [AALEB ] | none | Uninfected | ||
GSM2044946 | IFNγ only sample, rep 1 | bronchial epithelial cell line [AALEB ] | none | Uninfected | Extra interventions IFN gamma added |
|
GSM2044947 | IFNγ only sample, rep 2 | bronchial epithelial cell line [AALEB ] | none | Uninfected | Extra interventions IFN gamma added |
|
GSM2044948 | RSV only sample, rep 1 | bronchial epithelial cell line [AALEB ] | 48 hrs | RSV subtype A Memphis 37 | Human orthopneumovirus | |
GSM2044949 | RSV only sample, rep 2 | bronchial epithelial cell line [AALEB ] | 48 hrs | RSV subtype A Memphis 37 | Human orthopneumovirus | |
GSM2044950 | RSV & IFNγ sample, rep 1 | bronchial epithelial cell line [AALEB ] | 48 hrs | RSV subtype A Memphis 37 | Human orthopneumovirus | Extra interventions IFN gamma added |
GSM2044951 | RSV & IFNγ sample, rep 2 | bronchial epithelial cell line [AALEB ] | 48 hrs | RSV subtype A Memphis 37 | Human orthopneumovirus | Extra interventions IFN gamma added |