Virus Expression Database

GSE82160

FAS signalling in retroviral neuroinflammation

Submitted by Tim Dierckx (KU Leuven, Belgium) on Jun 02 2016

Platform: microarray – [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]

Pubmed: 28261198, 29872426

Summary We comprehensively explored Fas expression (protein and mRNA) and function in lymphocyte activation, apoptosis, proliferation and transcriptome, using flow cytometry, [3H]-thymidine incorporation and microarray analysis in PBMC from HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) patients.

15 Samples

ID Title Cell Type Timepoint Reported Virus Virus Species Exclusion Reason
GSM2185132 9325 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Data failed QC
At least 40% of samples in study failed QC
GSM2185133 9326 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Data failed QC
At least 40% of samples in study failed QC
GSM2185134 9330 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Data failed QC
all_probeset_mad_residual_mean is 0.926328 (poor normalization, above threshold of 0.80)
GSM2185135 9329 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Data failed QC
At least 40% of samples in study failed QC
GSM2185136 9331 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Data failed QC
At least 40% of samples in study failed QC
GSM2185137 9332 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Data failed QC
all_probeset_mad_residual_mean is 0.876681 (poor normalization, above threshold of 0.80)
GSM2185138 9307 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Data failed QC
all_probeset_mad_residual_mean is 0.824902 (poor normalization, above threshold of 0.80)
GSM2185139 9308 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Extra interventions
aFas antagonist
GSM2185140 9309 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Extra interventions
aFas agonist
GSM2185141 9313 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Data failed QC
all_probeset_mad_residual_mean is 0.834417 (poor normalization, above threshold of 0.80)
GSM2185142 9314 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Extra interventions
aFas antagonist
GSM2185143 9315 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Extra interventions
aFas agonist
GSM2185144 11787 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Data failed QC
all_probeset_mad_residual_mean is 0.804863 (poor normalization, above threshold of 0.80)
GSM2185145 11788 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Extra interventions
aFas antagonist
GSM2185146 11789 peripheral blood mononuclear cell  patient HTLV-1 Primate T-lymphotropic virus 1 Extra interventions
aFas agonist