Virus Expression Database

GSE92521

Analysis of parent-of-origin bias in gene expression levels

Submitted by Andrew Sharp (Icahn School of Medicine at Mount Sinai, USA) on Dec 16 2016

Platform: ngs – Illumina HiSeq 2000 (Homo sapiens)

Pubmed: 31234833

Summary In order to study parent-of-origin effects on gene expression, we performed RNAseq analysis (100bp single end reads) of 165 children who formed part of mother/father/child trios where genotype data was available from the HapMap and/or 1000 Genomes Projects. Based on phased genotypes at heterozygous SNP positions, we generated allelic counts for expression of the maternal and paternal alleles in each individual. This analysis reveals significant bias in the expression of the parental alleles for dozens of genes, including both previously known and novel imprinted transcripts.

165 Samples

ID Title Cell Type Timepoint Reported Virus Virus Species Exclusion Reason
GSM2431181 HG00405 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431182 HG00408 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431183 HG00420 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431184 HG00423 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431185 HG00429 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431186 HG00438 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431187 HG00444 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431188 HG00447 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431189 HG00450 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431190 HG00453 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431191 HG00459 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431192 HG00465 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431193 HG00474 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431194 HG00477 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431195 HG00480 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431196 HG00502 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431197 HG00514 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431198 HG00526 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431199 HG00532 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431200 HG00535 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431201 HG00538 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431202 HG00544 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431203 HG00558 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431204 HG00561 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431205 HG00567 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431206 HG00579 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431207 HG00582 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431208 HG00585 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431209 HG00591 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431210 HG00594 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431211 HG00597 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431212 HG00609 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431213 HG00612 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431214 HG00615 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431215 HG00621 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431216 HG00627 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431217 HG00630 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431218 HG00636 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431219 HG00652 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431220 HG00655 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431221 HG00658 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431222 HG00664 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431223 HG00673 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431224 HG00685 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431225 HG00691 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431226 HG00694 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431227 HG00700 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431228 HG00703 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431229 HG00706 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431230 HG00709 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431231 NA06991 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431232 NA06995 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431233 NA06997 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431234 NA07014 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431235 NA07019 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431236 NA07029 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431237 NA07048 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431238 NA07348 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431239 NA07349 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431240 NA10830 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431241 NA10831 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431242 NA10835 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431243 NA10836 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431244 NA10837 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431245 NA10838 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431246 NA10839 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431247 NA10840 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431248 NA10842 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431249 NA10843 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431250 NA10845 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431251 NA10846 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431252 NA10847 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431253 NA10851 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431254 NA10854 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431255 NA10855 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431256 NA10856 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431257 NA10857 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431258 NA10859 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431259 NA10860 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431260 NA10861 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431261 NA10863 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431262 NA10864 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431263 NA10865 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431264 NA12329 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431265 NA12335 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431266 NA12336 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431267 NA12344 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431268 NA12375 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431269 NA12376 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431270 NA12386 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431271 NA12485 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431272 NA12707 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431273 NA12739 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431274 NA12740 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431275 NA12752 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431276 NA12753 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431277 NA12766 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431278 NA12767 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431279 NA12801 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431280 NA12802 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431281 NA12817 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431282 NA12818 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431283 NA12832 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431284 NA12864 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431285 NA12865 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431286 NA12877 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431287 NA12878 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431288 NA18484 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431289 NA18485 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431290 NA18497 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431291 NA18500 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431292 NA18503 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431293 NA18506 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431294 NA18515 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431295 NA18518 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431296 NA18521 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431297 NA18854 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431298 NA18857 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431299 NA18860 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431300 NA18863 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431301 NA18869 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431302 NA18872 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431303 NA18875 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431304 NA18911 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431305 NA18914 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431306 NA18925 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431307 NA18930 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431308 NA18935 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431309 NA19094 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431310 NA19097 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431311 NA19100 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431312 NA19103 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431313 NA19109 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431314 NA19115 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431315 NA19120 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431316 NA19123 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431317 NA19129 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431318 NA19132 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431319 NA19139 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431320 NA19142 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431321 NA19145 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431322 NA19148 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431323 NA19151 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431324 NA19154 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431325 NA19161 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431326 NA19173 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431327 NA19174 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431328 NA19177 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431329 NA19180 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431330 NA19183 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431331 NA19186 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431332 NA19191 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431333 NA19194 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431334 NA19199 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431335 NA19202 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431336 NA19205 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431337 NA19208 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431338 NA19211 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431339 NA19215 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431340 NA19221 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431341 NA19224 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431342 NA19237 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431343 NA19240 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431344 NA19249 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4
GSM2431345 NA19258 lymphoblastoid cell line  immortalized Human gammaherpesvirus 4